3D Molecularly Functionalized Cell‐Free Biomimetic Scaffolds for Osteochondral Regeneration

• Published in: Advanced functional materials Vol. 29; no. 6
• Main Authors: Li, Lan, Li, Jiayi, Guo, Jiamin, Zhang, Huikang, Zhang, Xin, Yin, Caiyun, Wang, Liming, Zhu, Yishen, Yao, Qingqiang
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc 01.02.2019
• Subjects: 3D‐printed scaffolds; Biocompatibility; Biomedical materials; biomimetic scaffolds; Biomimetics; Cartilage; Coating; Defects; Differentiation (biology); Glutamic acid; Hydrogels; Implantation; Knee; Lysine; Materials science; osteochondral regeneration; Phenylalanine; Polycaprolactone; Regeneration (physiology); Repair; Scaffolds; self‐assembling peptide; Stem cells; Stiffness; Surgical implants; Three dimensional printing; Tissue engineering

Clinically, cartilage damage is frequently accompanied with subchondral bone injuries caused by disease or trauma. However, the construction of biomimetic scaffolds to support both cartilage and subchondral bone regeneration remains a great challenge. Herein, a novel strategy is adopted to realize t...