Self‐Mineralized Photothermal Bacteria Hybridizing with Mitochondria‐Targeted Metal–Organic Frameworks for Augmenting Photothermal Tumor Therapy

• Published in: Advanced functional materials Vol. 30; no. 14
• Main Authors: Chen, Qi‐Wen, Liu, Xin‐Hua, Fan, Jin‐Xuan, Peng, Si‐Yuan, Wang, Jia‐Wei, Wang, Xia‐Nan, Zhang, Cheng, Liu, Chuan‐Jun, Zhang, Xian‐Zheng
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc 01.04.2020
• Subjects: Adenosine triphosphate; Bacteria; cancer therapy; Encapsulation; Heat shock proteins; Heat tolerance; heat‐shock protein; Imidazole; Materials science; Metal-organic frameworks; Methylene blue; Mitochondria; Nanoparticles; Palladium; photothermal therapy; Singlet oxygen; Tumors

A photothermal bacterium (PTB) is reported for tumor‐targeted photothermal therapy (PTT) by using facultative anaerobic bacterium Shewanella oneidensis MR‐1 (S. oneidensis MR‐1) to biomineralize palladium nanoparticles (Pd NPs) on its surface without affecting bacterial activity. It is found that PT...