Metal‐free Dehydrogenation of Substituted Cyclohexanones to Phenols

• Published in: Advanced synthesis & catalysis Vol. 365; no. 8; pp. 1158 - 1164
• Main Authors: Leng, Li‐Jing, Zhang, De‐Long, Zhang, Liang, Lin, Xiao‐Long, Cai, Tian, Tan, Jian‐Ping, Luo, Qun‐Li
• Format: Journal Article
• Language: English
• Published: WEINHEIM Wiley 25.04.2023; Wiley Subscription Services, Inc
• Subjects: Carbonyls; Catalysis; Chemical synthesis; Chemistry; Chemistry, Applied; Chemistry, Organic; Cyclohexanone; Dehydrogenation; Desaturation; Iodine; Oxidation; Phenols; Physical Sciences; Raw materials; Reagents; Science & Technology; Substitutes; Substrates; Dehydrogenation; CONVERSION; Phenols; ENONES; Oxidation; Catalysis; CATALYZED AEROBIC DEHYDROGENATION; AROMATIZATION; ALPHA-IODINATION; Iodine

The preparation of substituted phenols via a direct carbonyl desaturation is an intrinsic challenging task in modern synthetic chemistry. Herein, we develop a modular catalytic protocol for the synthesis of substituted phenols via the direct dehydrogenative aromatization of simple cyclohexanones in...