Bile acid malabsorption in inflammatory bowel disease: Assessment by serum markers

• Published in: Inflammatory bowel diseases Vol. 17; no. 6; pp. 1322 - 1327
• Main Authors: Lenicek, Martin, Duricova, Dana, Komarek, Viktor, Gabrysova, Bronislava, Lukas, Milan, Smerhovsky, Zdenek, Vitek, Libor
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.06.2011
• Subjects: 7α‐hydroxycholest‐4‐en‐3‐one; Adult; Algorithms; bile acid malabsorption; Bile acids; Bile Acids and Salts - metabolism; Biomarkers - blood; Case-Control Studies; Cholesterol - blood; Cholesterol, HDL - blood; Chromatography, High Pressure Liquid; Colitis, Ulcerative - blood; Colitis, Ulcerative - complications; Colitis, Ulcerative - surgery; Crohn Disease - blood; Crohn Disease - complications; Crohn Disease - surgery; Crohn's disease; Enzyme-Linked Immunosorbent Assay; Female; Fibroblast growth factor; Fibroblast Growth Factors - blood; Humans; ileal disease; Ileitis; Ileum; inflammatory bowel disease; Inflammatory bowel diseases; Inflammatory Bowel Diseases - blood; Inflammatory Bowel Diseases - complications; Inflammatory Bowel Diseases - surgery; International organizations; Intestine; Malabsorption; Malabsorption Syndromes - blood; Malabsorption Syndromes - complications; Male; Middle Aged; Serum levels; Severity of Illness Index; Surgery; Ulcerative colitis

Background: Bile acid malabsorption (BAM) is a common feature of Crohn's disease (CD). We aimed to determine whether BAM develops only in patients with a resected distal ileum or if it also occurs in patients who have not undergone surgery for CD. Methods: The study included 347 patients with C...