Low cell pH depresses peak power in rat skeletal muscle fibres at both 30°C and 15°C: implications for muscle fatigue

• Published in: The Journal of physiology Vol. 575; no. 3; pp. 887 - 899
• Main Authors: Knuth, S. T., Dave, H., Peters, J. R., Fitts, R. H.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.09.2006; Blackwell Science Inc
• Subjects: Skeletal Muscle and Exercise

Historically, an increase in intracellular H+ (decrease in cell pH) was thought to contribute to muscle fatigue by direct inhibition of the cross‐bridge leading to a reduction in velocity and force. More recently, due to the observation that the effects were less at temperatures closer to those obse...