Artemsieverolactones A—H, Eight Guaiane‐Type Sesquiterpenoid Trimers from Artemisia sieversiana

• Published in: Chinese journal of chemistry Vol. 42; no. 10; pp. 1084 - 1092
• Main Authors: Dong, Wei, Huang, Xiao‐Yan, Li, Tian‐Ze, Weng, Yan‐Mei, Geng, Chang‐An, Chen, Ji‐Jun
• Format: Journal Article
• Language: English
• Published: Weinheim WILEY‐VCH Verlag GmbH & Co. KGaA 15.05.2024; Wiley; Wiley Subscription Services, Inc
• Subjects: Antihepatic fibrosis; Artemisia sieversiana; Artemsieverolactones A—H; Cancer; Chemistry; Chemistry, Multidisciplinary; Collagen (type I); Cycloaddition; Extracellular matrix; Fibrosis; Guaiane‐type sesquiterpenoid trimers; Hyaluronic acid; Laminin; NMR spectroscopy; Physical Sciences; Science & Technology; Trimers; X-ray diffraction; Antihepatic fibrosis; ACTIVATION; Artemsieverolactones A-H; Guaiane-type sesquiterpenoid trimers; LIVER FIBROSIS; X-ray diffraction; RATS; Artemisia sieversiana; Extracellular matrix; DIMERIC GUAIANOLIDES; NMR spectroscopy; Cancer

Comprehensive Summary Eight new guaiane‐type sesquiterpenoid trimers, artemsieverolactones A—H, possessing unprecedented scaffolds via biocatalyzed [4+2] Diels−Alder cycloaddition reactions were identified from Artemisia sieversiana. Their structures were determined by comprehensive spectroscopic da...