Naltrexone treatment of comorbid alcohol and cocaine use disorders

• Published in: Psychopharmacology Vol. 139; no. 1-2; pp. 44 - 52
• Main Authors: Hersh, D, Van Kirk, J R, Kranzler, H R
• Format: Journal Article
• Language: English
• Published: Germany Springer Nature B.V 01.09.1998
• Subjects: Adult; Alcohol; Alcohol Deterrents - therapeutic use; Alcohol Drinking - drug therapy; Alcoholism - complications; Alcoholism - drug therapy; Clinical trials; Cocaine; Cocaine-Related Disorders - complications; Cocaine-Related Disorders - drug therapy; Comorbidity; Compliance; Dosage; Double-Blind Method; Drug dependence; Female; Humans; Male; Naltrexone; Naltrexone - therapeutic use; Placebos

Naltrexone (NTX) has been shown to be efficacious for the treatment of alcohol dependence. Since alcohol and cocaine use disorders commonly co-occur, we conducted a randomized, double-blind, placebo-controlled trial of NTX 50 mg/day in 64 subjects with comorbid alcohol and cocaine use disorders. Alt...