Randomized-Controlled Trial Examining the Effect of Pelvic Floor Muscle Training in the Treatment of Stress Urinary Incontinence in Men after a Laparoscopic Radical Prostatectomy Pilot Study

• Published in: Journal of clinical medicine Vol. 10; no. 13; p. 2946
• Main Authors: Strojek, Katarzyna, Weber-Rajek, Magdalena, Strączyńska, Agnieszka, Piekorz, Zuzanna, Pilarska, Beata, Jarzemski, Piotr, Kozakiewicz, Mariusz, Brzoszczyk, Bartosz, Jarzemski, Marcin, Styczyńska, Hanna, Goch, Aleksander, Radzimińska, Agnieszka
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 30.06.2021; MDPI
• Subjects: Antibodies; Bladder; Cancer surgery; Clinical medicine; Intervention; Laparoscopy; Medical research; Musculoskeletal system; Pelvis; Performance evaluation; Prostate cancer; Quality of life; Smooth muscle; Surgery; Surgical outcomes; Urinary incontinence; Urological surgery
• ISSN: 2077-0383; 2077-0383
• DOI: 10.3390/jcm10132946

Aim: The aim of this study was to assess the impact of pelvic floor muscle training (PMFT) in the treatment of stress urinary incontinence (SUI) in men after they received radical prostatectomy (RP). Methods: From November 2018 to September 2019, patients who underwent radical prostatectomy were assessed for eligibility. A total of 37 men were then randomly assigned to the experimental group (EG) and the control group (CG). The EG group received supervised exercise twice a week for 12 weeks, and the CG did not receive any intervention. To objectify the results obtained in both groups before and after the intervention, the authors assessed myostatin concentration. Moreover, the Expanded Prostate Cancer Index Composite (EPIC-26) was applied to assess the quality of life, and Beck’s Depression Inventory (BDI-II) was used to measure depression severity. Results: Study results demonstrated a statistically significant reduction of myostatin concentration in the EG following the treatment and no statistically significant differences in this parameter in the CG. In addition, a comparison of the EPIC-26 scores in the EG at the initial and final assessments revealed a statistically significant improvement in the quality of life in each domain. A comparison of the EPIC-26 scores in the CG at the initial and final assessments showed there is a statistically significant decline in quality of life in the “overall urinary problem” and “sexual” domain. A comparison of the BDI-II scores at the initial and final assessments showed a statistically significant decline in depressive symptoms in the EG and no statistically significant differences in the CG. Conclusions: PFMT is an effective treatment for urinary incontinence (UI) in men who received radical prostatectomy.