Efficacy of Bletilla striata polysaccharide on hydrogen peroxide-induced apoptosis of osteoarthritic chondrocytes

• Published in: Journal of polymer research Vol. 25; no. 2; pp. 1 - 10
• Main Authors: Lai, Yen-Liang, Lin, Yu-Ying, Sadhasivam, Subramaniam, Kuan, Che-Yung, Chi, Chih-ying, Dong, Guo-Chung, Lin, Feng-Huei
• Format: Journal Article
• Language: English
• Published: Dordrecht Springer Netherlands 01.02.2018; Springer Nature B.V
• Subjects: Antioxidants; Apoptosis; Biocompatibility; Biomedical materials; Cartilage; Characterization and Evaluation of Materials; Chemistry; Chemistry and Materials Science; Etiology; Gene expression; Heredity; Hydrogels; Hydrogen peroxide; Industrial Chemistry/Chemical Engineering; Infrared spectrometers; Narcotics; NMR; Nonsteroidal anti-inflammatory drugs; Nuclear magnetic resonance; Original Paper; Oxidative stress; Pain; Pharmacology; Polymer Sciences; Rheological properties; Topical Collection on Bio-Based Polymers; Toxicity; Wound healing; Cartilage; Polysaccharide hydrogel; Osteoarthritis; Chondrocytes

Osteoarthritis (OA) is a degenerative joint disease affecting millions of peoples worldwide. Though the etiology of OA includes joint injury, obesity, aging, and heredity, oxidative stress is majorly considered as the hallmark of OA initiation and clinical progression. Traditional pharmacologic ther...