Short‐chain fatty acids mediate gut microbiota–brain communication and protect the blood–brain barrier integrity - Chenghan, Mei; Wanxin, Li; Bangcheng, Zhao; Yao, He; Qinxi, Li; Ting, Zhang; Xiaojie, Li; Kun, Zhang; Yingqian, Zhang; Zhihui, Zhong (Annals of the New York Academy of Sciences, 2025)
Keywords: Acetic acid; Animals; Anti-Bacterial Agents - pharmacology; Antibiotics; Blood-brain barrier; Blood-Brain Barrier - drug effects; Blood-Brain Barrier - metabolism; Brain - metabolism; Central nervous system; Claudin-5 - genetics; Claudin-5 - metabolism; Dysbacteriosis; Dysbiosis - metabolism; Endothelial cells; Fatty acids; Fatty Acids, Volatile - metabolism; Fatty Acids, Volatile - pharmacology; Gastrointestinal Microbiome - drug effects; Gastrointestinal Microbiome - physiology; gut microbiome; Gut microbiota; Gut-brain axis; Humans; Integrity; Intestinal microflora; Macaca mulatta; Male; Membrane permeability; Mice; Mice, Inbred C57BL; Microbiota; Microorganisms; Monkeys; mRNA; Neurological diseases; Oral administration; propionate; Propionic acid; short‐chain fatty acids; Therapeutic targets; blood–brain barrier; gut microbiome; short‐chain fatty acids; antibiotics; propionate