Effects of the Fasting‐Postprandial State on Arterial Spin Labeling MRI‐Based Cerebral Perfusion Quantification in Alzheimer's Disease

• Published in: Journal of magnetic resonance imaging Vol. 60; no. 5; pp. 2173 - 2183
• Main Authors: Li, Runzhi, Zhuo, Zhizheng, Hong, Yin, Yao, Zeshan, Li, Zhaohui, Wang, Yanli, Jiang, Jiwei, Wang, Linlin, Jia, Ziyan, Sun, Mengfan, Zhang, Yuan, Li, Wenyi, Ren, Qiwei, Zhang, Yanling, Duan, Yunyun, Liu, Yi, Wei, Hongen, Zhang, Yechuan, Chappell, Michael, Shi, Hanping, Liu, Yaou, Xu, Jun
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 01.11.2024; Wiley Subscription Services, Inc
• Subjects: Aged; Alzheimer Disease - diagnostic imaging; Alzheimer Disease - physiopathology; Alzheimer's disease; Blood flow; Brain - blood supply; Brain - diagnostic imaging; Cerebral blood flow; Cerebrovascular Circulation - physiology; Cognitive ability; Cognitive Dysfunction - diagnostic imaging; cognitive function; Correlation analysis; Correlation coefficient; Correlation coefficients; Diagnosis; Diagnosis, Differential; Diagnostic systems; Differential diagnosis; Fasting; Female; Field strength; Humans; Image acquisition; Labeling; Magnetic Resonance Imaging - methods; Male; Medical imaging; Middle Aged; Neurodegenerative diseases; Neuroimaging; postprandial; Postprandial Period; Prospective Studies; Regional analysis; Regional development; Regression analysis; Regression models; Spin labeling; Spin Labels; Statistical analysis; Statistical models; Statistical tests; Support vector machines; Variance analysis; cognitive function; postprandial; cerebral blood flow; fasting; Alzheimer's disease

Background The fasting‐postprandial state remains an underrecognized confounding factor for quantifying cerebral blood flow (CBF) in the cognitive assessment and differential diagnosis of Alzheimer's disease (AD). Purpose To investigate the effects of fasting‐postprandial state on arterial spin...