Weekly Teriparatide Versus Bisphosphonate for Bone Union During 6 Months After Multi-Level Lumbar Interbody Fusion for Osteoporotic Patients: A Multicenter, Prospective, Randomized Study

• Published in: Spine (Philadelphia, Pa. 1976) Vol. 45; no. 13; p. 863
• Main Authors: Oba, Hiroki, Takahashi, Jun, Yokomichi, Hiroshi, Hasegawa, Tomohiko, Ebata, Shigeto, Mukaiyama, Keijiro, Ohba, Tetsuro, Ushirozako, Hiroki, Kuraishi, Shugo, Ikegami, Shota, Uehara, Masashi, Takizawa, Takashi, Munakata, Ryo, Hatakenaka, Terue, Matsuyama, Yukihiro, Haro, Hirotaka
• Format: Journal Article
• Language: English
• Published: United States 01.07.2020
• Subjects: Adult; Aged; Diphosphonates - therapeutic use; Female; Humans; Ilium - transplantation; Intervertebral Disc - drug effects; Intervertebral Disc - surgery; Joints; Lumbar Vertebrae - drug effects; Lumbar Vertebrae - surgery; Lumbosacral Region - surgery; Male; Middle Aged; Osteoporosis - surgery; Prospective Studies; Random Allocation; Spinal Fusion - methods; Teriparatide - therapeutic use; Treatment Outcome
• ISSN: 1528-1159
• DOI: 10.1097/BRS.0000000000003426

Multicenter, prospective randomized study. Evaluate the impact of weekly teriparatide (WT) and bone contact (BC) status of grafted bone in patients recovering from multilevel lumbar interbody fusion (M-LIF). WT has been reported to significantly improve bone fusion following posterior or transforami...