The effect of acute exercise on glycogen synthesis rate in obese subjects studied by 13C MRS

• Published in: European journal of applied physiology Vol. 111; no. 2; pp. 275 - 283
• Main Authors: van der Graaf, Marinette, de Haan, Jacco H., Smits, Paul, Mulder, Alexandra H., Heerschap, Arend, Tack, Cees J.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer-Verlag 01.02.2011; Springer
• Subjects: Adult; Basal Metabolism - physiology; Biological and medical sciences; Biomedical and Life Sciences; Biomedicine; Blood Glucose - metabolism; Carbon Isotopes - pharmacokinetics; Exercise - physiology; Exercise Therapy; Female; Fundamental and applied biological sciences. Psychology; Glycogen - biosynthesis; Human Physiology; Humans; Magnetic Resonance Spectroscopy - methods; Male; Middle Aged; Muscle, Skeletal - metabolism; Obesity - metabolism; Obesity - physiopathology; Obesity - therapy; Occupational Medicine/Industrial Medicine; Original; Original Article; Overweight - metabolism; Overweight - physiopathology; Sports Medicine; Time Factors; Vertebrates: body movement. Posture. Locomotion. Flight. Swimming. Physical exercise. Rest. Sports; Obesity; Insulin resistance; Glycogen synthesis rate; Muscle; Exercise; C magnetic resonance spectroscopy; Endocrinopathy; Physical exercise; Human; Glycogen; Acute; Magnetic resonance; Nutrition disorder; Metabolic diseases; Rhythm; Biosynthesis; Striated muscle; Target tissue resistance; Nutritional status

In obesity, insulin-stimulated glucose uptake in skeletal muscle is decreased. We investigated whether the stimulatory effect of acute exercise on glucose uptake and subsequent glycogen synthesis was normal. The study was performed on 18 healthy volunteers, 9 obese (BMI = 32.6 ± 1.2 kg/m 2 , mean ± ...