Practical synthesis of C -aryl glycosides via redox-neutral Borono–Catellani reaction

• Published in: Chemical communications (Cambridge, England) Vol. 61; no. 4; pp. 736 - 739
• Main Authors: Xu, Dekang, Li, Xia, Cui, Ziyang, Cao, Liming, Cheng, Hong-Gang, Zhou, Qianghui
• Format: Journal Article
• Language: English
• Published: CAMBRIDGE Royal Soc Chemistry 07.01.2025; Royal Society of Chemistry
• Subjects: Aromatic compounds; Chemical synthesis; Chemistry; Chemistry, Multidisciplinary; Esters; Functional groups; Glycosides; Physical Sciences; Science & Technology; NUCLEOPHILES; GLYCOSYLATION

Herein, we describe a practical Borono–Catellani strategy for the efficient synthesis of C -aryl glycosides, with readily available arylboronic esters and glycosyl chlorides as the building blocks. It features mild reaction conditions, excellent diastereoselectivities, and good functional group tole...