Sequence analysis of tumor necrosis factor-α (TNF-α) promoter, 5'UTR and exon1 and association of rs361525 (-238 G>A) with BMI

• Published in: Kuwait journal of science Vol. 50; no. 1 A; pp. 1 - 18
• Main Authors: al-Rashid, Maryam H., Husayn, Rubina F., al-Bustan, Suzanne A., Barhush, Sahar A.
• Format: Journal Article
• Language: English
• Published: Kuwait Kuwait University, Academic Publication Council 01.01.2023; Elsevier

Obesity is among the most common complex diseases with a high rate of morbidity and mortality globally and locally in Kuwait. Tumor Necrosis Factor-alpha (TNF-α) is a pro-inflammatory cytokine that is primarily secreted by monocytes/macrophage. Increased expression of TNF-α level had been observed i...