Noninvasive glucose measurement by fluorescence quenching of non toxic gold nanoparticles
Effects of interaction of human body compatible gold nanoparticles with glucose on fluorescence emission spectra of the nanoparticles are investigated experimentally. It is observed that nanoparticles’ fluorescence peak quenches and blue shifted because of such interaction. This procedure is sensiti...
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| Published in | Optics and laser technology Vol. 58; pp. 135 - 138 |
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| Main Authors | , , |
| Format | Journal Article |
| Language | English |
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Elsevier Ltd
01.06.2014
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| Abstract | Effects of interaction of human body compatible gold nanoparticles with glucose on fluorescence emission spectra of the nanoparticles are investigated experimentally. It is observed that nanoparticles’ fluorescence peak quenches and blue shifted because of such interaction. This procedure is sensitive even to low difference of glucose concentration. The results suggest that glucose could seriously affect the optical properties of gold nanoparticles. Furthermore, a linear range of relative shift of different fluorescence spectrum's peaks is obtained. Furthermore, comparison of fluorescence and absorption results shows that the former technique is as much as 20 times more sensitive to the variation of glucose concentration.
•We propose a precise, noninvasive method for glucose measurement with no infection.•We fabricate novel nontoxic gold nanoparticle to determine glucose concentration.•The effect of glucose on intensity and position of fluorescence peaks is examined.•Our technique is 20 times more sensitive to the variation of glucose concentration. |
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| AbstractList | Effects of interaction of human body compatible gold nanoparticles with glucose on fluorescence emission spectra of the nanoparticles are investigated experimentally. It is observed that nanoparticles’ fluorescence peak quenches and blue shifted because of such interaction. This procedure is sensitive even to low difference of glucose concentration. The results suggest that glucose could seriously affect the optical properties of gold nanoparticles. Furthermore, a linear range of relative shift of different fluorescence spectrum's peaks is obtained. Furthermore, comparison of fluorescence and absorption results shows that the former technique is as much as 20 times more sensitive to the variation of glucose concentration.
•We propose a precise, noninvasive method for glucose measurement with no infection.•We fabricate novel nontoxic gold nanoparticle to determine glucose concentration.•The effect of glucose on intensity and position of fluorescence peaks is examined.•Our technique is 20 times more sensitive to the variation of glucose concentration. |
| Author | Ghanavi, J. Bagheri, Z. Massudi, R. |
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| CitedBy_id | crossref_primary_10_1016_j_photonics_2015_04_006 crossref_primary_10_1007_s13738_015_0677_x crossref_primary_10_1177_0003702816653127 crossref_primary_10_3389_fbioe_2023_1168086 crossref_primary_10_1109_JSEN_2022_3151221 |
| Cites_doi | 10.1103/PhysRevB.77.115403 10.1364/OL.19.002170 10.1021/es401758d 10.1021/ja905793q 10.1016/S1748-0132(08)70014-8 10.1007/BF02458048 10.1073/pnas.96.12.6700 10.1007/s11671-010-9691-1 10.1016/j.aca.2013.02.025 10.1366/0003702021954557 10.1021/ac00213a021 10.1016/S0009-2614(99)01414-1 10.1103/PhysRevLett.89.203002 10.1021/ja00190a012 10.1016/j.optlaseng.2008.04.008 10.1016/0370-1573(84)90098-X 10.1111/j.1525-1594.1994.tb02230.x 10.1093/clinchem/45.2.165 10.1021/jo049147p 10.1103/PhysRevA.28.524 10.1007/s10812-009-9125-y 10.1089/dia.2004.6.660 10.1103/PhysRevLett.96.113002 |
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| Keywords | Fluorescence spectroscopy Non toxic gold nanoparticles Glucose |
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