Synthesis of chiral boranes via asymmetric insertion of carbenes into B–H bonds catalyzed by the rhodium( i ) diene complex

• Published in: Chemical communications (Cambridge, England) Vol. 60; no. 65; pp. 8601 - 8604
• Main Authors: Ankudinov, Nikita M., Komarova, Alina A., Podyacheva, Evgeniya S., Chusov, Denis A., Danshina, Anastasia A., Perekalin, Dmitry S.
• Format: Journal Article
• Language: English
• Published: CAMBRIDGE Royal Soc Chemistry 09.08.2024; Royal Society of Chemistry
• Subjects: Asymmetry; Boranes; Carbenes; Chemical bonds; Chemical synthesis; Chemistry; Chemistry, Multidisciplinary; Insertion; Physical Sciences; Rhodium; Science & Technology; Stereoselectivity

Molecules with chiral boron atoms have been scarcely studied due to limited synthetic access. Herein, we report a new method for their synthesis via asymmetric insertion of arydiazoacetates into the B–H bonds of prochiral carbene–boranes NHC–BH 2 R. The reaction is catalyzed by the rhodium( i ) comp...