Development of a wearable microfluidic amperometric sensor based on spatial three-electrode system for sweat glucose analysis

• Published in: Talanta (Oxford) Vol. 293; p. 128101
• Main Authors: Liu, Guodong, Dou, Xiaolong, Zhang, Pinna, Yin, Sijie, Tan, Qifeng, Jin, Xin, Li, Chaojiang, Zhang, Xianchao
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.10.2025
• Subjects: Amperometric sensor; Biosensing Techniques - instrumentation; Electrochemical Techniques - instrumentation; Electrodes; Glucose; Glucose - analysis; Humans; Lab-On-A-Chip Devices; Microfluidic Analytical Techniques - instrumentation; Spatial three-electrode system; Sweat - chemistry; Sweet; Wearable Electronic Devices; Wearable microfluidic sensor; Sweet; Glucose; Spatial three-electrode system; Amperometric sensor; Wearable microfluidic sensor

Most amperometric glucose sensors utilize nanomaterials to increase the surface area of the working electrode for sensitivity enhancement. However, this approach not only increases the cost and complicates the fabrication process, but also results in functional surfaces with limited durability. We p...