DNA nanolantern-based split aptamer probes for in situ ATP imaging in living cells and lighting up mitochondria

• Published in: Analyst (London) Vol. 146; no. 8; pp. 2600 - 2608
• Main Authors: Wang, Ya-Xin, Wang, Dong-Xia, Ma, Jia-Yi, Wang, Jing, Du, Yi-Chen, Kong, De-Ming
• Format: Journal Article
• Language: English
• Published: England Royal Society of Chemistry 26.04.2021
• Subjects: Adenosine Triphosphate; Aptamers, Nucleotide; Biocompatibility; Biosensing Techniques; Cells (biology); Crosslinking; DNA; DNA Probes; Energy transfer; Fluorescence; Lighting; Mitochondria

Accurate and specific analysis of adenosine triphosphate (ATP) expression levels in living cells can provide valuable information for understanding cell metabolism, physiological activities and pathologic mechanisms. Herein, DNA nanolantern-based split aptamer nanoprobes are prepared and demonstrate...