Quantitative susceptibility mapping in the human brain at 7T with phase‐cycled balanced SSFP

• Published in: Magnetic resonance in medicine Vol. 94; no. 4; pp. 1469 - 1484
• Main Authors: Acikgoz, Berk Can, Sainz Martinez, Cristina, Mackowiak, Adèle L. C., Plähn, Nils M. J., Safarkhanlo, Yasaman, Peper, Eva S., Radojewski, Piotr, Bonanno, Gabriele, Jorge, João, Bastiaansen, Jessica A. M.
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.10.2025
• Subjects: 7 T; Adult; Algorithms; balanced steady‐state free precession; Brain; Brain - diagnostic imaging; Brain mapping; Brain Mapping - methods; bSSFP; Caudate nucleus; Deviation; Feasibility; Female; Globus pallidus; Humans; Image Processing, Computer-Assisted - methods; Magnetic resonance imaging; Magnetic Resonance Imaging - methods; Male; Mapping; Phase matching; phase‐cycled bSSFP; Proton density (concentration); Putamen; QSM; quantitative MRI; Susceptibility; Thalamus; quantitative MRI; balanced steady‐state free precession; QSM; 7 T; phase‐cycled bSSFP; bSSFP

Purpose To demonstrate the feasibility of QSM and to show the potential of simultaneous T1$$ {T}_1 $$, T2$$ {T}_2 $$, and proton density (PD) mapping in the human brain at 7T based on phase‐cycled balanced SSFP (bSSFP) MRI. Methods An algorithm was developed to estimate off‐resonance frequency in mu...