Comparative Transcriptomics of Fat Bodies between Symbiotic and Quasi-Aposymbiotic Adult Females of Blattella germanica with Emphasis on the Metabolic Integration with Its Endosymbiont Blattabacterium and Its Immune System

• Published in: International journal of molecular sciences Vol. 25; no. 8; p. 4228
• Main Authors: Silva, Francisco J., Domínguez-Santos, Rebeca, Latorre, Amparo, García-Ferris, Carlos
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 11.04.2024
• Subjects: Amino acids; Ammonia; Animals; Antimicrobial agents; Antimicrobial Peptides - genetics; Antimicrobial Peptides - metabolism; Bacteria; Bacteroidetes - genetics; Bacteroidetes - metabolism; Cell division; Cockroaches; Fat Body - metabolism; Female; Gene Expression Profiling; Genes; Genomes; Immune System - metabolism; Infections; Insects; Membranes; Metabolism; Metabolites; Microbiota; Peptides; Symbiosis - genetics; Transcriptome; Uric acid; Blattabacterium; cuticle; transcriptome; peptidoglycan-recognition proteins; tyrosine metabolism; uricolytic pathway; metabolite transporters; Blattella germanica; antimicrobial peptides; fat body

We explored the metabolic integration of Blattella germanica and its obligate endosymbiont Blattabacterium cuenoti by the transcriptomic analysis of the fat body of quasi-aposymbiotic cockroaches, where the endosymbionts were almost entirely removed with rifampicin. Fat bodies from quasi-aposymbioti...