Enhanced drug retention by anthracene crosslinked nanocomposites for bimodal imaging-guided phototherapy

• Published in: Nanoscale Vol. 13; no. 35; pp. 14713 - 14722
• Main Authors: Fan, Xiaoshan, Ke, Lingjie, Cheng, Hongwei, Chen, Hu, Li, Zhiguo, Ye, Enyi, Loh, Xian-Jun, Wu, Yun-Long, Liu, Gang, Li, Zibiao
• Format: Journal Article
• Language: English
• Published: Cambridge Royal Society of Chemistry 17.09.2021
• Subjects: Anthracene; Biomedical materials; Contrast agents; Crosslinking; Diagnosis; Dimers; Fluorescence; Light therapy; Magnetic resonance imaging; Medical imaging; Micelles; Nanocomposites; Nanoparticles; Near infrared radiation; Penetration depth; Photodynamic therapy; Photothermal conversion; Polymer coatings; Real time; Ultraviolet radiation

Efficient drug delivery, multifunctional combined therapy and real-time diagnosis are the main hallmarks in the exploitation of precision nanomedicine. Herein, an anthracene-functionalized micelle containing a magnetic resonance imaging (MRI) contrast agent, upconversion nanoparticles (UCNPs) and th...