KTP laser alone or combined with bleomycin for pharyngolaryngeal hemangioma: a lesion grade-based determination of prognosis

• Published in: Acta oto-laryngologica Vol. 143; no. 6; pp. 518 - 523
• Main Authors: Shu, Min, He, Peijie, Wei, Chunsheng
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis 01.06.2023
• Subjects: Adult; Anesthesia, General; Bleomycin - therapeutic use; hemangioma; Hemangioma - surgery; Humans; larynx; Laser Therapy - methods; Lasers, Solid-State - therapeutic use; pharynx; Potassium titanyl phosphate laser; treatment; Treatment Outcome; hemangioma; larynx; treatment; pharynx; Potassium titanyl phosphate laser
• ISSN: 0001-6489; 1651-2251
• DOI: 10.1080/00016489.2023.2220744

No standard potassium titanyl phosphate (KTP) laser treatment strategy is available yet for pharyngolaryngeal hemangioma. To explore the therapeutic effect of KTP laser, alone or combined with bleomycin injection, for pharyngolaryngeal hemangioma. This observational study included patients with pharyngolaryngeal hemangioma treated between May 2016 and November 2021: KTP laser under local anesthesia, KTP laser under general anesthesia, or KTP laser combined with bleomycin injection under general anesthesia. A total of 60 patients were recruited, including 17, 19, and 24 patients with grade 1, 2, and 3 hemangiomas, respectively. A total of 21 patients underwent KTP laser under local anesthesia, 31 underwent KTP laser under general anesthesia, and 8 underwent KTP laser under general anesthesia combined with bleomycin. The cure rates were 100%, 89.5%, and 20.8% for grade 1, 2, and 3 lesions, respectively. The prognosis was significantly different among the grades of hemangioma (p < .001). KTP laser treatment might be an effective treatment for adult patients with pharyngolaryngeal hemangioma. The size of the hemangioma might be the major factor influencing the prognosis. The method of anesthesia and whether it was combined with bleomycin injection might not affect the prognosis.