Parameter estimation in nonlinear mixed effect models based on ordinary differential equations: an optimal control approach - Clairon, Quentin; Pasin, Chloé; Balelli, Irene; Thiébaut, Rodolphe; Prague, Mélanie (Computational statistics, 2024)
Keywords: Accuracy; Approximation; Cost function; Differential equations; Economic Theory/Quantitative Economics/Mathematical Methods; Epidemiology; Initial conditions; Mathematics and Statistics; Maximum likelihood estimation; Maximum likelihood method; Nonlinear control; Optimal control; Ordinary differential equations; Original Paper; Parameter estimation; Parameter identification; Pharmacodynamics; Pharmacokinetics; Probability and Statistics in Computer Science; Probability Theory and Stochastic Processes; Statistics; Virology; Mechanistic models; Clinical trial analysis; Ordinary differential equations; Optimal control theory; Nonlinear mixed effects models; Dynamic population models