A subunit vaccine based on Brucella rBP26 induces Th1 immune responses and M1 macrophage activation - Wen, Jia; Li, Zihua; Lv, Yongxue; Ding, Shuqin; Zhu, Yazhou; Yang, Jihui; Tang, Jing; Zhu, Mingxing; Zhao, Yinqi; Zhao, Wei (Acta biochimica et biophysica Sinica, 2024)
Keywords: Adjuvants, Immunologic - pharmacology; Animals; Bacterial Proteins - genetics; Bacterial Proteins - immunology; BP26; Brucella - immunology; Brucella Vaccine - immunology; Brucellosis - immunology; Brucellosis - prevention & control; CD8-Positive T-Lymphocytes - immunology; Cytokines - immunology; Cytokines - metabolism; Female; immunogenicity; M1 macrophage; Macrophage Activation - drug effects; Macrophage Activation - immunology; Macrophages - immunology; Membrane Proteins; Mice; Mice, Inbred BALB C; Oligodeoxyribonucleotides - immunology; recombinant protein vaccine; Th1 Cells - immunology; Th1 immune responses; Vaccines, Subunit - immunology; Th1 immune responses; recombinant protein vaccine; M1 macrophage; BP26; immunogenicity