Differential contribution of protein phosphatase 1α to cell transformation of different cell types

• Published in: Oncology reports Vol. 42; no. 4; pp. 1598 - 1608
• Main Authors: Chen, Jo‑Mei, Chen, Kun‑Chieh, Chiu, Shao‑Chih, Chen, Ru‑Yi, Hsia, Jiun‑Yi, Huang, Yun‑Ru, Yu, Chang‑Tze
• Format: Journal Article
• Language: English
• Published: Greece Spandidos Publications UK Ltd 01.10.2019
• Subjects: Androgens; Biotechnology; Breast cancer; Cell adhesion & migration; Cell culture; Cell growth; Deoxyribonucleic acid; DNA; Esophagus; Immunoglobulins; Kinases; Leukemia; Liver cancer; Lung cancer; Lymphoma; Penicillin; Phosphatase; Prostate cancer; Proteins; Studies

Protein phosphorylation plays roles in cell transformation. Numerous protein kinase enzymes actively participate in the formation of various types of cancer by phosphorylating downstream substrates. Aurora‑A is a widely known Serine/Threonine (Ser/Thr) oncogenic kinase, which is upregulated in more...