MR Elastography–derived Stiffness: A Biomarker for Intervertebral Disc Degeneration

• Published in: Radiology Vol. 285; no. 1; pp. 167 - 175
• Main Authors: Walter, Benjamin A., Mageswaran, Prasath, Mo, Xiaokui, Boulter, Daniel J., Mashaly, Hazem, Nguyen, Xuan V., Prevedello, Luciano M., Thoman, William, Raterman, Brian D., Kalra, Prateek, Mendel, Ehud, Marras, William S., Kolipaka, Arunark
• Format: Journal Article
• Language: English
• Published: United States Radiological Society of North America 01.10.2017
• Subjects: Adult; Aged; Biomarkers; Cross-Sectional Studies; Elasticity Imaging Techniques - methods; Humans; Image Interpretation, Computer-Assisted; Intervertebral Disc - diagnostic imaging; Intervertebral Disc - physiopathology; Intervertebral Disc Degeneration - diagnostic imaging; Intervertebral Disc Degeneration - physiopathology; Magnetic Resonance Imaging - methods; Middle Aged; Original Research; Young Adult
• ISSN: 0033-8419; 1527-1315; 1527-1315
• DOI: 10.1148/radiol.2017162287

Purpose To determine the repeatability of magnetic resonance (MR) elastography-derived shear stiffness measurements of the intervertebral disc (IVD) taken throughout the day and their relationship with IVD degeneration and subject age. Materials and Methods In a cross-sectional study, in vivo lumbar...