Changes in Inflammation, Oxidative Stress, Mitochondrial DNA Content after Rosiglitazone in HIV Lipoatrophy

• Published in: Journal of AIDS & clinical research Vol. 3; no. 8; p. 174
• Main Authors: Tungsiripat, Marisa, El-Bejjani, Dalia, Rizk, Nesrine, Hu, Bo, Ross, Allison C, Walker, Ulrich A, Lebrecht, Dirk, Milne, Ginger, Storer, Norma, McComsey, Grace A
• Format: Journal Article
• Language: English
• Published: United States 01.01.2012

OBJECTIVE: We aim to evaluate the mechanisms of rosiglitazone-induced fat recovery in HIV+ patients with lipoatrophy on thymidine Nucleoside Reverse Transcriptase Inhibitors (NRTI) sparing regimens. METHOD: Measures of limb fat (DXA), oxidative stress (F2 isoprostanes) and inflammation [High-sensiti...