Cerebral ischemia-induced angiogenesis is dependent on tumor necrosis factor receptor 1-mediated upregulation of α5β1 and αVβ3 integrins - Huang, Heng; Huang, Qijuan; Wang, Fuxin; Milner, Richard; Li, Longxuan (Journal of neuroinflammation, 2016)
Keywords: Animals; Antibodies - pharmacology; Brain - cytology; Cell Proliferation - drug effects; Cells, Cultured; Cytokines - genetics; Cytokines - metabolism; Disease Models, Animal; Endothelial Cells - drug effects; Endothelial Cells - metabolism; Humans; Infarction, Middle Cerebral Artery - complications; Integrin alpha5beta1 - immunology; Integrin alpha5beta1 - metabolism; Integrin alphaVbeta3 - immunology; Integrin alphaVbeta3 - metabolism; Male; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic - etiology; Neovascularization, Pathologic - metabolism; Receptors, Tumor Necrosis Factor, Type I - immunology; Receptors, Tumor Necrosis Factor, Type I - metabolism; Receptors, Tumor Necrosis Factor, Type II - genetics; Receptors, Tumor Necrosis Factor, Type II - immunology; Receptors, Tumor Necrosis Factor, Type II - metabolism; Signal Transduction - drug effects; Transcriptional Activation - drug effects; Up-Regulation - drug effects; Angiogenesis; Cerebral ischemia; Integrin; Tumor necrosis factor-α