Association study of apelin-APJ system genetic polymorphisms with incident metabolic syndrome in a Chinese population: a case-control study

• Published in: Oncotarget Vol. 10; no. 38; pp. 3807 - 3817
• Main Authors: Zhang, Meijin, Peng, Feng, Lin, Liming, Yu, Mingzhong, Huang, Chengyuan, Hu, Dan, Guo, Qinghui, Xu, Changsheng, Lin, Jinxiu
• Format: Journal Article
• Language: English
• Published: United States Impact Journals LLC 04.06.2019
• Subjects: Research Paper; metabolic syndrome; APJ; apelin; single nucleotide polymorphism

Apelin-APJ system has been implicated in the regulation of metabolic homeostasis. This study aimed to explore the genetic predisposition of the apelin-APJ system to metabolic syndrome. 1005 subjects were enrolled, including 448 metabolic syndrome patients and 557 controls. Seven single nucleotide po...