Targeted protein quantitation in human body fluids by mass spectrometry
Human body fluids (biofluids) contain various proteins, some of which reflect individuals' physiological conditions or predict diseases. Therefore, the analysis of biofluids can provide substantial information on novel biomarkers for clinical diagnosis and prognosis. In the past decades, mass s...
Saved in:
| Published in | Mass spectrometry reviews Vol. 42; no. 6; pp. e21788 - 2403 |
|---|---|
| Main Authors | , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
Wiley Subscription Services, Inc
01.11.2023
|
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | Human body fluids (biofluids) contain various proteins, some of which reflect individuals' physiological conditions or predict diseases. Therefore, the analysis of biofluids can provide substantial information on novel biomarkers for clinical diagnosis and prognosis. In the past decades, mass spectrometry (MS)-based technologies have been developed as proteomic strategies not only for the identification of protein biomarkers but also for biomarker verification/validation in body fluids for clinical applications. The main advantage of targeted MS-based methodologies is the accurate and specific simultaneous quantitation of multiple biomarkers with high sensitivity. Here, we review MS-based methodologies that are currently used for the targeted quantitation of protein components in human body fluids, especially in plasma, urine, cerebrospinal fluid, and saliva. In addition, the currently used MS-based methodologies are summarized with a specific focus on applicable clinical sample types, MS configurations, and acquisition modes. |
|---|---|
| AbstractList | Abstract
Human body fluids (biofluids) contain various proteins, some of which reflect individuals' physiological conditions or predict diseases. Therefore, the analysis of biofluids can provide substantial information on novel biomarkers for clinical diagnosis and prognosis. In the past decades, mass spectrometry (MS)‐based technologies have been developed as proteomic strategies not only for the identification of protein biomarkers but also for biomarker verification/validation in body fluids for clinical applications. The main advantage of targeted MS‐based methodologies is the accurate and specific simultaneous quantitation of multiple biomarkers with high sensitivity. Here, we review MS‐based methodologies that are currently used for the targeted quantitation of protein components in human body fluids, especially in plasma, urine, cerebrospinal fluid, and saliva. In addition, the currently used MS‐based methodologies are summarized with a specific focus on applicable clinical sample types, MS configurations, and acquisition modes. Human body fluids (biofluids) contain various proteins, some of which reflect individuals' physiological conditions or predict diseases. Therefore, the analysis of biofluids can provide substantial information on novel biomarkers for clinical diagnosis and prognosis. In the past decades, mass spectrometry (MS)-based technologies have been developed as proteomic strategies not only for the identification of protein biomarkers but also for biomarker verification/validation in body fluids for clinical applications. The main advantage of targeted MS-based methodologies is the accurate and specific simultaneous quantitation of multiple biomarkers with high sensitivity. Here, we review MS-based methodologies that are currently used for the targeted quantitation of protein components in human body fluids, especially in plasma, urine, cerebrospinal fluid, and saliva. In addition, the currently used MS-based methodologies are summarized with a specific focus on applicable clinical sample types, MS configurations, and acquisition modes. |
| Author | Chen, Yi-Ting Wang, Hsueh-Ting Liao, Wan-Rou Chen, Sung-Fang Chen, Hsiao-Wei |
| Author_xml | – sequence: 1 givenname: Yi-Ting surname: Chen fullname: Chen, Yi-Ting organization: Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan – sequence: 2 givenname: Wan-Rou surname: Liao fullname: Liao, Wan-Rou organization: Department of Chemistry, National Taiwan Normal University, Taipei, Taiwan – sequence: 3 givenname: Hsueh-Ting surname: Wang fullname: Wang, Hsueh-Ting organization: Instrumentation Center, National Taiwan Normal University, Taipei, Taiwan – sequence: 4 givenname: Hsiao-Wei surname: Chen fullname: Chen, Hsiao-Wei organization: Molecular and Medicine Research Center, Chang Gung University, Taoyuan, Taiwan – sequence: 5 givenname: Sung-Fang surname: Chen fullname: Chen, Sung-Fang organization: Instrumentation Center, National Taiwan Normal University, Taipei, Taiwan |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/35702881$$D View this record in MEDLINE/PubMed |
| BookMark | eNpdkD1PwzAQhi1URD9g4A-gSCwwpPjsxB8jqqAgVWIps-U4DqRK4tZ2hvx7Ai0MTKeTHr333jNHk851FqFrwEvAmDy0OiwJcCHO0AywFCnhgk_QDBPOU44pn6J5CDuMAXKACzSlOcdECJih9Vb7Dxttmey9i7bukkOvu1hHHWvXJeP-2be6SwpXDknV9HUZkmJIxoshCXtronetjX64ROeVboK9Os0Fen9-2q5e0s3b-nX1uEkNBRpTYaTMJK5KRgmurMzBGK0ZFyXPqCwsZphDwUkupbEGADKT4xI0yyDTlaV0ge6OuWPdQ29DVG0djG0a3VnXB0UYZ5JQwtiI3v5Dd6733dhOEcEpJwznYqTuj5TxLgRvK7X3dav9oACrb7tq_FX92B3Zm1NiX7S2_CN_ddIvbr115w |
| CitedBy_id | crossref_primary_10_1016_j_trac_2023_117234 crossref_primary_10_1186_s12014_023_09407_y crossref_primary_10_1186_s12886_024_03292_1 |
| Cites_doi | 10.1038/ki.2015.267 10.3122/jabfm.2008.06.070080 10.1016/j.jprot.2014.10.017 10.1194/jlr.P083576 10.1021/pr3008732 10.1016/j.jprot.2018.02.026 10.1007/s40120-019-00165-4 10.1021/ac5033066 10.1371/journal.pone.0221024 10.4155/bio-2017-0218 10.1016/j.bbrc.2021.01.082 10.1039/9781849734363-00271 10.1074/mcp.RA118.000718 10.1021/acs.jproteome.5b01119 10.1016/j.celrep.2020.108402 10.1074/mcp.M900254-MCP200 10.1194/jlr.D064618 10.1016/j.jprot.2019.103571 10.1021/acs.analchem.1c03243 10.1016/j.neulet.2014.04.041 10.1016/j.cca.2015.12.020 10.1021/ac200812d 10.1021/pr101148r 10.15252/msb.20156297 10.1155/2013/701247 10.1021/acs.analchem.1c01246 10.1074/mcp.M800238-MCP200 10.1016/j.aca.2017.01.059 10.1021/pr100576x 10.1002/1873-3468.13487 10.1073/pnas.0403453101 10.1016/j.oraloncology.2015.08.008 10.1074/mcp.M113.028365 10.1073/pnas.1612368113 10.1212/WNL.0000000000008081 10.1016/j.ijrobp.2016.06.008 10.1016/j.jprot.2015.02.010 10.4155/bio-2016-0059 10.1016/j.talanta.2020.121718 10.1016/j.jprot.2013.07.026 10.1016/j.ymeth.2015.04.001 10.1021/acs.jproteome.7b00467 10.1016/bs.mie.2015.09.022 10.1002/pmic.201500433 10.1016/j.jprot.2011.12.031 10.1074/mcp.M116.064758 10.1373/clinchem.2010.153767 10.1136/bmjdrc-2019-001152 10.1002/jcla.20028 10.1186/s12967-018-1388-8 10.15252/msb.20178126 10.1021/pr060305y 10.1111/cas.14881 10.1016/j.vascn.2014.09.008 10.18632/oncotarget.17463 10.1016/j.kint.2015.12.049 10.1016/j.aca.2012.02.017 10.1074/mcp.RA119.001530 10.1016/j.nrleng.2018.03.006 10.1074/mcp.M113.034660 10.1002/prca.201700157 10.1074/mcp.RA117.000147 10.1016/bs.acc.2018.12.001 10.1007/s12192-018-0902-5 10.18632/oncotarget.24578 10.1016/j.mcpro.2021.100165 10.1021/acs.jproteome.1c00657 10.1016/j.aca.2019.12.006 10.1016/j.clgc.2012.06.003 10.1007/s00401-014-1266-2 10.1074/mcp.O112.019802 10.1002/pmic.201100568 10.1021/pr401060x 10.1007/978-1-4939-7253-1_29 10.1186/s12967-018-1669-2 10.1002/pmic.201800135 10.1002/prca.201500135 10.1074/mcp.M800446-MCP200 10.1186/s40035-020-00188-0 10.1016/j.cll.2011.07.005 10.1016/j.aca.2014.06.024 10.1021/ja00475a072 10.1074/mcp.M111.013854 10.1021/pr201068b 10.1021/pr5010828 10.1038/ncomms11906 10.1177/0004563215593561 10.1021/acs.jproteome.9b00772 10.1038/s41598-020-61496-z 10.1371/journal.pone.0233443 10.1371/journal.pone.0193799 10.1002/pmic.200300661 10.4168/aair.2021.13.1.5 10.1002/prca.201700039 10.1016/j.jprot.2013.04.024 10.1038/bjc.2017.365 10.1186/s12014-016-9121-1 10.1186/s41016-020-00190-5 10.1021/pr3008144 10.4155/bio.15.228 10.1016/j.dib.2018.03.036 10.1002/pmic.202100153 10.1021/acs.analchem.7b01878 10.1074/mcp.M112.018861 10.1002/pmic.201600230 10.1074/mcp.M113.028639 10.3389/fimmu.2018.02756 10.1002/prca.201600132 10.18632/oncotarget.13634 10.1016/j.cca.2015.05.022 10.3390/proteomes5040031 10.1155/2019/8094049 10.1074/mcp.M800460-MCP200 10.1038/s41598-018-33280-7 10.1016/j.talanta.2021.122102 10.3389/fnins.2020.00526 10.1074/mcp.M300031-MCP200 10.1038/nbt.1661 10.1016/j.ebiom.2018.03.009 10.1021/pr500317d 10.5772/23715 10.3390/ijms161226120 10.1002/pmic.201500543 10.18632/oncotarget.21710 10.1586/14789450.2013.858022 10.1186/s12014-020-09283-w 10.1002/pmic.201200316 10.1177/104063871102300119 10.1002/pmic.201400382 10.1016/j.jalz.2017.06.2266 10.1021/acs.analchem.0c02563 10.1021/acs.jproteome.6b00979 10.1021/acs.analchem.1c02349 10.1038/s41598-020-64483-6 10.3389/fmed.2021.548212 10.1073/pnas.0832254100 10.1021/pr101052y 10.1016/j.jprot.2020.104067 10.1021/pr034086h 10.1002/prca.201500020 10.1016/j.bonr.2019.100238 10.1002/jcla.22058 10.1074/mcp.r200007-mcp200 10.1002/prca.202000012 |
| ContentType | Journal Article |
| Copyright | 2022 John Wiley & Sons Ltd. 2023 John Wiley & Sons Ltd. |
| Copyright_xml | – notice: 2022 John Wiley & Sons Ltd. – notice: 2023 John Wiley & Sons Ltd. |
| DBID | NPM AAYXX CITATION K9. 7X8 |
| DOI | 10.1002/mas.21788 |
| DatabaseName | PubMed CrossRef ProQuest Health & Medical Complete (Alumni) MEDLINE - Academic |
| DatabaseTitle | PubMed CrossRef ProQuest Health & Medical Complete (Alumni) MEDLINE - Academic |
| DatabaseTitleList | CrossRef PubMed ProQuest Health & Medical Complete (Alumni) |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Physics |
| EISSN | 1098-2787 |
| EndPage | 2403 |
| ExternalDocumentID | 10_1002_mas_21788 35702881 |
| Genre | Journal Article Review |
| GroupedDBID | --- .3N .GA 05W 0R~ 10A 1L6 1OB 1OC 1ZS 33P 3SF 3WU 4.4 50Y 50Z 51W 51X 52M 52N 52O 52P 52S 52T 52U 52W 52X 5GY 5RE 5VS 66C 702 7PT 8-0 8-1 8-3 8-4 8-5 8UM 930 A03 AAESR AAEVG AAHHS AANLZ AAONW AAXRX AAZKR ABCQN ABCUV ABDBF ABIJN ABJNI ABPVW ACAHQ ACCFJ ACCZN ACGFS ACPOU ACPRK ACXBN ACXQS ADBBV ADEOM ADIZJ ADKYN ADMGS ADOZA ADXAS ADZMN AEEZP AEIGN AEIMD AENEX AEQDE AEUQT AEUYR AFBPY AFFPM AFGKR AFPWT AFZJQ AHBTC AHMBA AITYG AIURR AIWBW AJBDE AJXKR ALAGY ALMA_UNASSIGNED_HOLDINGS ALUQN AMBMR AMYDB ATUGU AUFTA AZBYB AZVAB BAFTC BFHJK BHBCM BMNLL BMXJE BNHUX BROTX BRXPI BY8 CS3 D-E D-F DCZOG DPXWK DR1 DR2 DRFUL DRSTM DU5 EBD EBS F00 F01 F04 F5P G-S G.N GNP GODZA H.T H.X HBH HGLYW HHY HHZ HZ~ IX1 J0M JPC KQQ LATKE LAW LC2 LC3 LEEKS LH4 LITHE LOXES LP6 LP7 LUTES LYRES MEWTI MK4 MRFUL MRSTM MSFUL MSSTM MXFUL MXSTM N04 N05 N9A NF~ NNB NPM O66 O9- OIG P2P P2W P2X P4D PQQKQ Q.N Q11 QB0 QRW R.K RNS ROL RWI RX1 RYL SUPJJ TN5 UB1 V2E W8V W99 WBFHL WBKPD WH7 WIB WIH WIK WJL WOHZO WQJ WRC WRJ WXSBR WYISQ XG1 XPP XV2 ZZTAW ~02 ~IA ~KM ~WT .Y3 31~ 53G AASGY AAYXX ABEML ABTAH ACBWZ ACSCC AQPKS ASPBG AVWKF AZFZN BDRZF CITATION EJD FEDTE HF~ HVGLF LH5 LW6 PALCI RIWAO RJQFR SAMSI ZY4 K9. 7X8 |
| ID | FETCH-LOGICAL-c313t-8c99490fd6320fe951ccaa678d7439be06071b72599cec1114c50d1a6414afe33 |
| ISSN | 0277-7037 |
| IngestDate | Fri Aug 16 22:14:09 EDT 2024 Wed Nov 06 09:09:57 EST 2024 Fri Aug 23 02:24:09 EDT 2024 Sat Sep 28 08:18:41 EDT 2024 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 6 |
| Language | English |
| License | 2022 John Wiley & Sons Ltd. |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-c313t-8c99490fd6320fe951ccaa678d7439be06071b72599cec1114c50d1a6414afe33 |
| Notes | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 |
| PMID | 35702881 |
| PQID | 2873726058 |
| PQPubID | 1016389 |
| PageCount | 25 |
| ParticipantIDs | proquest_miscellaneous_2676923266 proquest_journals_2873726058 crossref_primary_10_1002_mas_21788 pubmed_primary_35702881 |
| PublicationCentury | 2000 |
| PublicationDate | 2023-11-01 |
| PublicationDateYYYYMMDD | 2023-11-01 |
| PublicationDate_xml | – month: 11 year: 2023 text: 2023-11-01 day: 01 |
| PublicationDecade | 2020 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States – name: Hoboken |
| PublicationTitle | Mass spectrometry reviews |
| PublicationTitleAlternate | Mass Spectrom Rev |
| PublicationYear | 2023 |
| Publisher | Wiley Subscription Services, Inc |
| Publisher_xml | – name: Wiley Subscription Services, Inc |
| References | e_1_2_9_75_1 e_1_2_9_98_1 e_1_2_9_52_1 e_1_2_9_79_1 e_1_2_9_94_1 e_1_2_9_10_1 e_1_2_9_56_1 e_1_2_9_90_1 e_1_2_9_71_1 e_1_2_9_103_1 e_1_2_9_126_1 e_1_2_9_107_1 e_1_2_9_122_1 e_1_2_9_145_1 e_1_2_9_14_1 e_1_2_9_141_1 e_1_2_9_37_1 Carroll M. F. (e_1_2_9_18_1) 2000; 62 e_1_2_9_41_1 e_1_2_9_64_1 e_1_2_9_87_1 e_1_2_9_22_1 e_1_2_9_45_1 e_1_2_9_68_1 e_1_2_9_83_1 e_1_2_9_6_1 e_1_2_9_119_1 e_1_2_9_60_1 e_1_2_9_2_1 e_1_2_9_138_1 e_1_2_9_111_1 e_1_2_9_134_1 e_1_2_9_115_1 e_1_2_9_26_1 e_1_2_9_49_1 e_1_2_9_130_1 e_1_2_9_30_1 e_1_2_9_53_1 e_1_2_9_72_1 e_1_2_9_11_1 e_1_2_9_34_1 e_1_2_9_57_1 e_1_2_9_95_1 e_1_2_9_76_1 e_1_2_9_91_1 e_1_2_9_102_1 e_1_2_9_148_1 e_1_2_9_129_1 e_1_2_9_144_1 e_1_2_9_106_1 e_1_2_9_15_1 e_1_2_9_38_1 e_1_2_9_140_1 e_1_2_9_121_1 e_1_2_9_19_1 e_1_2_9_42_1 e_1_2_9_88_1 e_1_2_9_61_1 e_1_2_9_46_1 e_1_2_9_84_1 Zhao L. (e_1_2_9_149_1) 2011; 53 Teimoury A. (e_1_2_9_125_1) 2014; 5 e_1_2_9_23_1 e_1_2_9_65_1 e_1_2_9_80_1 e_1_2_9_5_1 e_1_2_9_114_1 e_1_2_9_137_1 e_1_2_9_118_1 e_1_2_9_133_1 e_1_2_9_9_1 e_1_2_9_27_1 e_1_2_9_69_1 e_1_2_9_110_1 e_1_2_9_31_1 e_1_2_9_50_1 e_1_2_9_73_1 e_1_2_9_35_1 e_1_2_9_77_1 e_1_2_9_96_1 e_1_2_9_12_1 e_1_2_9_54_1 e_1_2_9_92_1 e_1_2_9_109_1 e_1_2_9_101_1 e_1_2_9_128_1 e_1_2_9_105_1 e_1_2_9_124_1 e_1_2_9_147_1 e_1_2_9_39_1 e_1_2_9_120_1 e_1_2_9_16_1 e_1_2_9_58_1 e_1_2_9_143_1 e_1_2_9_20_1 e_1_2_9_62_1 e_1_2_9_89_1 e_1_2_9_24_1 e_1_2_9_43_1 e_1_2_9_66_1 e_1_2_9_85_1 e_1_2_9_8_1 e_1_2_9_81_1 e_1_2_9_4_1 e_1_2_9_113_1 Critselis E. (e_1_2_9_33_1) 2016; 31 e_1_2_9_117_1 e_1_2_9_136_1 e_1_2_9_28_1 e_1_2_9_47_1 e_1_2_9_132_1 e_1_2_9_74_1 e_1_2_9_51_1 e_1_2_9_78_1 e_1_2_9_13_1 e_1_2_9_32_1 e_1_2_9_55_1 e_1_2_9_97_1 Park S. A. (e_1_2_9_99_1) 2020; 10 e_1_2_9_93_1 e_1_2_9_108_1 e_1_2_9_70_1 e_1_2_9_127_1 e_1_2_9_100_1 e_1_2_9_123_1 e_1_2_9_104_1 e_1_2_9_146_1 e_1_2_9_17_1 e_1_2_9_36_1 e_1_2_9_59_1 e_1_2_9_142_1 e_1_2_9_63_1 e_1_2_9_40_1 e_1_2_9_21_1 e_1_2_9_67_1 e_1_2_9_44_1 e_1_2_9_86_1 e_1_2_9_7_1 e_1_2_9_82_1 e_1_2_9_3_1 e_1_2_9_112_1 e_1_2_9_139_1 e_1_2_9_116_1 e_1_2_9_135_1 e_1_2_9_25_1 e_1_2_9_131_1 e_1_2_9_48_1 e_1_2_9_29_1 e_1_2_9_150_1 |
| References_xml | – ident: e_1_2_9_37_1 doi: 10.1038/ki.2015.267 – volume: 5 start-page: 341 issue: 3 year: 2014 ident: e_1_2_9_125_1 article-title: Why 24‐h urine albumin excretion rate method still is used for screening of diabetic nephropathy in Isfahan laboratories? publication-title: Int J Prev Med contributor: fullname: Teimoury A. – ident: e_1_2_9_88_1 doi: 10.3122/jabfm.2008.06.070080 – ident: e_1_2_9_114_1 doi: 10.1016/j.jprot.2014.10.017 – ident: e_1_2_9_12_1 doi: 10.1194/jlr.P083576 – ident: e_1_2_9_19_1 doi: 10.1021/pr3008732 – ident: e_1_2_9_64_1 doi: 10.1016/j.jprot.2018.02.026 – ident: e_1_2_9_92_1 doi: 10.1007/s40120-019-00165-4 – ident: e_1_2_9_21_1 doi: 10.1021/ac5033066 – ident: e_1_2_9_43_1 doi: 10.1371/journal.pone.0221024 – ident: e_1_2_9_83_1 doi: 10.4155/bio-2017-0218 – ident: e_1_2_9_115_1 doi: 10.1016/j.bbrc.2021.01.082 – ident: e_1_2_9_26_1 doi: 10.1039/9781849734363-00271 – ident: e_1_2_9_13_1 doi: 10.1074/mcp.RA118.000718 – ident: e_1_2_9_35_1 doi: 10.1021/acs.jproteome.5b01119 – ident: e_1_2_9_116_1 doi: 10.1016/j.celrep.2020.108402 – ident: e_1_2_9_137_1 doi: 10.1074/mcp.M900254-MCP200 – ident: e_1_2_9_34_1 doi: 10.1194/jlr.D064618 – ident: e_1_2_9_27_1 doi: 10.1016/j.jprot.2019.103571 – ident: e_1_2_9_128_1 doi: 10.1021/acs.analchem.1c03243 – ident: e_1_2_9_97_1 doi: 10.1016/j.neulet.2014.04.041 – ident: e_1_2_9_52_1 doi: 10.1016/j.cca.2015.12.020 – ident: e_1_2_9_8_1 doi: 10.1021/ac200812d – ident: e_1_2_9_96_1 doi: 10.1021/pr101148r – ident: e_1_2_9_50_1 doi: 10.15252/msb.20156297 – ident: e_1_2_9_59_1 doi: 10.1155/2013/701247 – ident: e_1_2_9_143_1 doi: 10.1021/acs.analchem.1c01246 – ident: e_1_2_9_47_1 doi: 10.1074/mcp.M800238-MCP200 – ident: e_1_2_9_132_1 doi: 10.1016/j.aca.2017.01.059 – ident: e_1_2_9_23_1 doi: 10.1021/pr100576x – volume: 62 start-page: 1333 issue: 6 year: 2000 ident: e_1_2_9_18_1 article-title: Proteinuria in adults: A diagnostic approach publication-title: Am erican Family Physician contributor: fullname: Carroll M. F. – ident: e_1_2_9_46_1 doi: 10.1002/1873-3468.13487 – ident: e_1_2_9_107_1 doi: 10.1073/pnas.0403453101 – ident: e_1_2_9_140_1 doi: 10.1016/j.oraloncology.2015.08.008 – ident: e_1_2_9_130_1 doi: 10.1074/mcp.M113.028365 – ident: e_1_2_9_146_1 doi: 10.1073/pnas.1612368113 – ident: e_1_2_9_117_1 doi: 10.1212/WNL.0000000000008081 – ident: e_1_2_9_67_1 doi: 10.1016/j.ijrobp.2016.06.008 – ident: e_1_2_9_45_1 doi: 10.1016/j.jprot.2015.02.010 – ident: e_1_2_9_111_1 doi: 10.4155/bio-2016-0059 – ident: e_1_2_9_2_1 doi: 10.1016/j.talanta.2020.121718 – ident: e_1_2_9_101_1 doi: 10.1016/j.jprot.2013.07.026 – ident: e_1_2_9_104_1 doi: 10.1016/j.ymeth.2015.04.001 – ident: e_1_2_9_118_1 doi: 10.1021/acs.jproteome.7b00467 – ident: e_1_2_9_119_1 doi: 10.1016/bs.mie.2015.09.022 – ident: e_1_2_9_89_1 doi: 10.1002/pmic.201500433 – ident: e_1_2_9_24_1 doi: 10.1016/j.jprot.2011.12.031 – ident: e_1_2_9_25_1 doi: 10.1074/mcp.M116.064758 – ident: e_1_2_9_105_1 doi: 10.1373/clinchem.2010.153767 – ident: e_1_2_9_65_1 doi: 10.1136/bmjdrc-2019-001152 – ident: e_1_2_9_77_1 doi: 10.1002/jcla.20028 – ident: e_1_2_9_134_1 doi: 10.1186/s12967-018-1388-8 – ident: e_1_2_9_75_1 doi: 10.15252/msb.20178126 – ident: e_1_2_9_57_1 doi: 10.1021/pr060305y – ident: e_1_2_9_127_1 doi: 10.1111/cas.14881 – ident: e_1_2_9_71_1 doi: 10.1016/j.vascn.2014.09.008 – ident: e_1_2_9_98_1 doi: 10.18632/oncotarget.17463 – ident: e_1_2_9_122_1 doi: 10.1016/j.kint.2015.12.049 – ident: e_1_2_9_141_1 doi: 10.1016/j.aca.2012.02.017 – ident: e_1_2_9_30_1 doi: 10.1074/mcp.RA119.001530 – ident: e_1_2_9_4_1 doi: 10.1016/j.nrleng.2018.03.006 – ident: e_1_2_9_15_1 doi: 10.1074/mcp.M113.034660 – ident: e_1_2_9_110_1 doi: 10.1002/prca.201700157 – ident: e_1_2_9_54_1 doi: 10.1074/mcp.RA117.000147 – ident: e_1_2_9_87_1 doi: 10.1016/bs.acc.2018.12.001 – ident: e_1_2_9_74_1 doi: 10.1007/s12192-018-0902-5 – ident: e_1_2_9_129_1 doi: 10.18632/oncotarget.24578 – ident: e_1_2_9_131_1 doi: 10.1016/j.mcpro.2021.100165 – ident: e_1_2_9_36_1 doi: 10.1021/acs.jproteome.1c00657 – ident: e_1_2_9_56_1 doi: 10.1016/j.aca.2019.12.006 – ident: e_1_2_9_70_1 doi: 10.1016/j.clgc.2012.06.003 – ident: e_1_2_9_81_1 doi: 10.1007/s00401-014-1266-2 – volume: 10 start-page: 1 issue: 1 year: 2020 ident: e_1_2_9_99_1 article-title: SWATH‐MS analysis of cerebrospinal fluid to generate a robust battery of biomarkers for Alzheimer's disease publication-title: Scientific Reports contributor: fullname: Park S. A. – ident: e_1_2_9_48_1 doi: 10.1074/mcp.O112.019802 – ident: e_1_2_9_40_1 doi: 10.1002/pmic.201100568 – ident: e_1_2_9_82_1 doi: 10.1021/pr401060x – ident: e_1_2_9_72_1 doi: 10.1007/978-1-4939-7253-1_29 – ident: e_1_2_9_133_1 doi: 10.1186/s12967-018-1669-2 – ident: e_1_2_9_112_1 doi: 10.1002/pmic.201800135 – ident: e_1_2_9_85_1 doi: 10.1002/prca.201500135 – ident: e_1_2_9_7_1 doi: 10.1074/mcp.M800446-MCP200 – ident: e_1_2_9_9_1 doi: 10.1186/s40035-020-00188-0 – ident: e_1_2_9_41_1 doi: 10.1016/j.cll.2011.07.005 – ident: e_1_2_9_58_1 doi: 10.1016/j.aca.2014.06.024 – ident: e_1_2_9_145_1 doi: 10.1021/ja00475a072 – ident: e_1_2_9_66_1 doi: 10.1074/mcp.M111.013854 – ident: e_1_2_9_17_1 doi: 10.1021/pr201068b – ident: e_1_2_9_63_1 doi: 10.1021/pr5010828 – ident: e_1_2_9_61_1 doi: 10.1038/ncomms11906 – ident: e_1_2_9_136_1 doi: 10.1177/0004563215593561 – ident: e_1_2_9_39_1 doi: 10.1021/acs.jproteome.9b00772 – ident: e_1_2_9_79_1 doi: 10.1038/s41598-020-61496-z – volume: 31 start-page: 249 issue: 2 year: 2016 ident: e_1_2_9_33_1 article-title: Utility of the CKD273 peptide classifier in predicting chronic kidney disease progression publication-title: Nephrology Dialysis Transplantation contributor: fullname: Critselis E. – ident: e_1_2_9_113_1 doi: 10.1371/journal.pone.0233443 – ident: e_1_2_9_86_1 doi: 10.1371/journal.pone.0193799 – ident: e_1_2_9_106_1 doi: 10.1002/pmic.200300661 – ident: e_1_2_9_29_1 doi: 10.4168/aair.2021.13.1.5 – ident: e_1_2_9_55_1 doi: 10.1002/prca.201700039 – ident: e_1_2_9_20_1 doi: 10.1016/j.jprot.2013.04.024 – ident: e_1_2_9_73_1 doi: 10.1038/bjc.2017.365 – ident: e_1_2_9_84_1 doi: 10.1186/s12014-016-9121-1 – ident: e_1_2_9_139_1 doi: 10.1186/s41016-020-00190-5 – ident: e_1_2_9_144_1 doi: 10.1021/pr3008144 – ident: e_1_2_9_53_1 doi: 10.4155/bio.15.228 – ident: e_1_2_9_93_1 doi: 10.1016/j.dib.2018.03.036 – ident: e_1_2_9_68_1 doi: 10.1002/pmic.202100153 – ident: e_1_2_9_90_1 doi: 10.1021/acs.analchem.7b01878 – ident: e_1_2_9_123_1 doi: 10.1074/mcp.M112.018861 – ident: e_1_2_9_102_1 doi: 10.1002/pmic.201600230 – ident: e_1_2_9_51_1 doi: 10.1074/mcp.M113.028639 – ident: e_1_2_9_32_1 doi: 10.3389/fimmu.2018.02756 – ident: e_1_2_9_138_1 doi: 10.1002/prca.201600132 – ident: e_1_2_9_120_1 doi: 10.18632/oncotarget.13634 – ident: e_1_2_9_142_1 doi: 10.1016/j.cca.2015.05.022 – volume: 53 year: 2011 ident: e_1_2_9_149_1 article-title: Quantification of proteins using peptide immunoaffinity enrichment coupled with mass spectrometry publication-title: Journal of Visualized Experiments contributor: fullname: Zhao L. – ident: e_1_2_9_80_1 doi: 10.3390/proteomes5040031 – ident: e_1_2_9_91_1 doi: 10.1155/2019/8094049 – ident: e_1_2_9_28_1 doi: 10.1074/mcp.M800460-MCP200 – ident: e_1_2_9_31_1 doi: 10.1038/s41598-018-33280-7 – ident: e_1_2_9_22_1 doi: 10.1016/j.talanta.2021.122102 – ident: e_1_2_9_76_1 doi: 10.3389/fnins.2020.00526 – ident: e_1_2_9_126_1 doi: 10.1074/mcp.M300031-MCP200 – ident: e_1_2_9_42_1 doi: 10.1038/nbt.1661 – ident: e_1_2_9_147_1 doi: 10.1016/j.ebiom.2018.03.009 – ident: e_1_2_9_103_1 doi: 10.1021/pr500317d – ident: e_1_2_9_10_1 doi: 10.5772/23715 – ident: e_1_2_9_109_1 doi: 10.3390/ijms161226120 – ident: e_1_2_9_14_1 doi: 10.1002/pmic.201500543 – ident: e_1_2_9_121_1 doi: 10.18632/oncotarget.21710 – ident: e_1_2_9_69_1 doi: 10.1586/14789450.2013.858022 – ident: e_1_2_9_78_1 doi: 10.1186/s12014-020-09283-w – ident: e_1_2_9_100_1 doi: 10.1002/pmic.201200316 – ident: e_1_2_9_3_1 doi: 10.1177/104063871102300119 – ident: e_1_2_9_62_1 doi: 10.1002/pmic.201400382 – ident: e_1_2_9_95_1 doi: 10.1016/j.jalz.2017.06.2266 – ident: e_1_2_9_60_1 doi: 10.1021/acs.analchem.0c02563 – ident: e_1_2_9_44_1 doi: 10.1021/acs.jproteome.6b00979 – ident: e_1_2_9_150_1 doi: 10.1021/acs.analchem.1c02349 – ident: e_1_2_9_38_1 doi: 10.1038/s41598-020-64483-6 – ident: e_1_2_9_124_1 doi: 10.3389/fmed.2021.548212 – ident: e_1_2_9_49_1 doi: 10.1073/pnas.0832254100 – ident: e_1_2_9_148_1 doi: 10.1021/pr101052y – ident: e_1_2_9_108_1 doi: 10.1016/j.jprot.2020.104067 – ident: e_1_2_9_6_1 doi: 10.1021/pr034086h – ident: e_1_2_9_16_1 doi: 10.1002/prca.201500020 – ident: e_1_2_9_135_1 doi: 10.1016/j.bonr.2019.100238 – ident: e_1_2_9_11_1 doi: 10.1002/jcla.22058 – ident: e_1_2_9_5_1 doi: 10.1074/mcp.r200007-mcp200 – ident: e_1_2_9_94_1 doi: 10.1002/prca.202000012 |
| SSID | ssj0011511 |
| Score | 2.4796107 |
| SecondaryResourceType | review_article |
| Snippet | Human body fluids (biofluids) contain various proteins, some of which reflect individuals' physiological conditions or predict diseases. Therefore, the... Abstract Human body fluids (biofluids) contain various proteins, some of which reflect individuals' physiological conditions or predict diseases. Therefore,... |
| SourceID | proquest crossref pubmed |
| SourceType | Aggregation Database Index Database |
| StartPage | e21788 |
| SubjectTerms | Biomarkers Body fluids Cerebrospinal fluid Mass spectroscopy Proteomics Quantitation Saliva |
| Title | Targeted protein quantitation in human body fluids by mass spectrometry |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/35702881 https://www.proquest.com/docview/2873726058 https://search.proquest.com/docview/2676923266 |
| Volume | 42 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3Nb9MwFLfKEBKXiW_KxmQQtykjiR03OaIJViHBYeq0cYpsxxGVRoJoctj-CP7mvWc7bjqKNLhESZw4rd_P78N-H4S8q0Q207mWkWaZijhYtZEq6iyKK1VLVZvCGOsg-1XMz_jni-xiMvk98lrqO3Wkr7fGlfwPVeEe0BWjZP-BsqFTuAHnQF84AoXheDcaWzdug5H-LVatxBDJpvNZt3Elw1XgU211dVhf9stqhdrmD9CXD22EJaYq6DZjor_cbvTBLUH1PvbhHN-WwU9iMYg_dOxZSrv4ei6b0H7a9ut1e8db5kDt71s7GPqfr7Cn4YlzsxyvT6TMB-qt2RhuEgNfcWLVODaLWUzTmRe1ng_zdIS3DabKXL0ZL6Axg-BW5u-SycIgHoGd5YoFbibYviX4gjuiS92clvBqaV-9R-6nwLjstv9pSEcGyrOt5xz-0ZCpKk7fh69u6jd_MVqs8rJ4RHa91UE_OAg9JhPTPCEPrPevXj0lJwOQqAcSHQOJwrUFEkUgUQckqq4oAomOsfKMnH36uDieR77CBkzNhHVRrouCF3FdCZbGMDGzBCa0BP2lQjtVmRizD6oZmMiFNhrEItdZXCVS8ITL2jD2nOw0bWNeEsq1YKC-56oWBQf2lBuw26TIq7wSsebZlLwdxqX86RKplH-M-5TsDyNW-nkGLTmWUsLt-yl5E5qBC-LWlmxM28Mz6KkNxoEQU_LCjXT4CstmoETnyau7_II98nAN4n2y0_3qzWtQOzt1YLFwA8x8gE0 |
| link.rule.ids | 315,783,787,27936,27937 |
| linkProvider | Wiley-Blackwell |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Targeted+protein+quantitation+in+human+body+fluids+by+mass+spectrometry&rft.jtitle=Mass+spectrometry+reviews&rft.au=Chen%2C+Yi%E2%80%90Ting&rft.au=Liao%2C+Wan%E2%80%90Rou&rft.au=Wang%2C+Hsueh%E2%80%90Ting&rft.au=Chen%2C+Hsiao%E2%80%90Wei&rft.date=2023-11-01&rft.issn=0277-7037&rft.eissn=1098-2787&rft.volume=42&rft.issue=6&rft.spage=2379&rft.epage=2403&rft_id=info:doi/10.1002%2Fmas.21788&rft.externalDBID=n%2Fa&rft.externalDocID=10_1002_mas_21788 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0277-7037&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0277-7037&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0277-7037&client=summon |