Assignment of the human gene for muscle-type phosphofructokinase (PFKM) to chromosome 1 (region cen leads to q32) using somatic cell hybrids and monoclonal anti-M antibody

• Published in: Somatic cell genetics Vol. 8; no. 1; p. 95
• Main Authors: Vora, S, Durham, S, de Martinville, B, George, D L, Francke, U
• Format: Journal Article
• Language: English
• Published: United States 01.01.1982
• Subjects: Antibodies, Monoclonal; Chromosome Mapping; Chromosomes, Human, 1-3; Genes; Humans; Muscles - enzymology; Phosphofructokinase-1 - genetics; Phosphofructokinase-1 - immunology

Human phosphofructokinase (PFK; EC 2.7.1.11) is under the control of three structural loci which encode muscle-type (M), live-type (L), and platelet-type (P) subunits; human diploid fibroblasts and leukocytes express all three loci. In order to assign human PFKM locus to a specific chromosome we hav...