Atractylodes macrocephala Koidz polysaccharide ameliorates DSS-induced colitis in mice by regulating the gut microbiota and tryptophan metabolism - Zhang, Qian-Wen; Yang, Meng-Jiao; Liao, Chun-Yu; Taha, Reham; Li, Qing-Yu; Abdelmotalab, Mohammed Ismail; Zhao, Si-Yu; Xu, Yan; Jiang, Zhen-Zhou; Chu, Cheng-Han; Huang, Xin; Jiao, Chun-Hua; et al. (British journal of pharmacology, 2025)
Keywords: Animals; Atractylodes - chemistry; Colitis - chemically induced; Colitis - drug therapy; Colitis - metabolism; Colitis - microbiology; Dextran Sulfate; Gastrointestinal Microbiome - drug effects; Male; Mice; Mice, Inbred C57BL; Polysaccharides - isolation & purification; Polysaccharides - pharmacology; Polysaccharides - therapeutic use; Receptors, Aryl Hydrocarbon - metabolism; Tryptophan - metabolism; gut microbiota‐derived tryptophan metabolites; Atractylodes macrocephala Koidz polysaccharide; pregnane X receptor; ulcerative colitis; gut microbiota