Natural and Semi-Synthetic Flavonoid Anti-SARS-CoV-2 Agents for the Treatment of Long COVID-19 Disease and Neurodegenerative Disorders of Cognitive Decline

• Published in: Frontiers in bioscience (Elite edition) Vol. 14; no. 4; p. 27
• Main Authors: Melrose, James, Smith, Margaret M
• Format: Journal Article
• Language: English
• Published: Singapore IMR Press 09.10.2022
• Subjects: alzheimer's disease; anti-inflammatory; Anti-Inflammatory Agents - therapeutic use; anti-oxidant; anti-viral phytochemicals; Antiviral Agents - pharmacology; Antiviral Agents - therapeutic use; ards; chalcones; cognition and memory; Cognitive Dysfunction - drug therapy; COVID-19; flavones; Flavonoids - pharmacology; Flavonoids - therapeutic use; Humans; long covid disease; Molecular Docking Simulation; Neurodegenerative Diseases - drug therapy; neuroinflammation; neuroprotection; nrf2; parkinson's disease; Post-Acute COVID-19 Syndrome; SARS-CoV-2; chalcones; anti-viral phytochemicals; Parkinson's disease; anti-oxidant; long COVID disease; SARS-CoV-2; cognition and memory; Nrf2; neuroinflammation; neuroprotection; anti-inflammatory; flavones; Alzheimer's disease; ARDS

The aim of this review is to highlight the beneficial attributes of flavonoids, a diverse family of widely-distributed polyphenolic phytochemicals that have beneficial cell and tissue protective properties. Phytochemicals are widely distributed in plants, herbs and shrubs used in traditional complim...