Epigallocatechin‐Gallate: Unraveling Its Protective Mechanisms and Therapeutic Potential

• Published in: Cell biochemistry and function Vol. 43; no. 2; pp. e70056 - n/a
• Main Authors: Dong, Xiang‐Wen, Fang, Wen‐Lan, Li, Yun‐Hang, Chai, Yu‐Rong
• Format: Journal Article
• Language: English
• Published: England Wiley Subscription Services, Inc 01.02.2025
• Subjects: Animals; Anti-Inflammatory Agents - chemistry; Anti-Inflammatory Agents - pharmacology; Anti-Inflammatory Agents - therapeutic use; antioxidant; Antioxidants - chemistry; Antioxidants - pharmacology; Antioxidants - therapeutic use; anti‐inflammation; Autophagy; Bioavailability; Catechin; Catechin - analogs & derivatives; Catechin - chemistry; Catechin - pharmacology; Catechin - therapeutic use; Clinical trials; EGCG; Epigallocatechin gallate; Green tea; Histone deacetylase; Humans; Inflammation; Inflammation - drug therapy; Inflammation - metabolism; Oxidative stress; Oxidative Stress - drug effects; Polyphenols; Reactive oxygen species; Reactive Oxygen Species - metabolism; Sirt1; SIRT1 protein; Sirtuin 1 - metabolism; Tea; Therapeutic applications; antioxidant; Sirt1; autophagy; anti‐inflammation; EGCG

ABSTRACT Epigallocatechin‐gallate (EGCG), the predominant catechin in green tea, is a key constituent of tea polyphenols. Due to the EGCG's diverse biological activities of anti‐inflammatory, antioxidant, and so forth, green tea is believed to exert a positive influence on a variety of diseases...