The effects of incretin‐based therapies on weight reduction and metabolic parameters in children with obesity: A systematic review and meta‐analysis

• Published in: Obesity reviews Vol. 25; no. 4; pp. e13686 - n/a
• Main Authors: Wang, Jian‐Ying, Kang, Jyun‐Wei, Wu, Chih‐Yuan, Peng, Tzu‐Rong, Liao, Ling‐Mei, Lee, Ming‐Chia, Lee, Jen‐Ai, Chen, Shih‐Ming
• Format: Journal Article
• Language: English
• Published: England Wiley Subscription Services, Inc 01.04.2024
• Subjects: childhood obesity, T2D; Children; Clinical trials; Diabetes mellitus (non-insulin dependent); DPP‐4; GLP‐1; Glucagon; Heterogeneity; Hypoglycemia; incretin‐based therapy; Meta-analysis; Obesity; Pediatrics; Side effects; Systematic review; Weight; Weight control; Weight loss; Weight reduction; DPP-4; incretin-based therapy; GLP-1; childhood obesity, T2D

Summary Background Growing evidence indicates that incretin‐based therapies (IBTs), glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs), and dipeptidyl peptidase‐4 inhibitors (DPP4is) are effective and safe for treating pediatric obesity patients with or without type 2 diabetes. Therefore, we aime...