Network pharmacology analysis and experimental verification of the antitumor effect and molecular mechanism of isocryptomerin on HepG2 cells - Cao, Jing‐Long; Li, Shu‐Mei; Tang, Yan‐Jun; Hou, Wen‐Shuang; Wang, An‐Qi; Li, Tian‐Zhu; Jin, Cheng‐Hao (Drug development research, 2024)
Keywords: AKT protein; Anticancer properties; Antitumor activity; Apoptosis; Caspase; Cell adhesion & migration; cell apoptosis; Cell cycle; Cell migration; Cell viability; Cyclin D; Cyclin-dependent kinase inhibitor p27; EGFR; Epidermal growth factor receptors; Flavonoids; G1 phase; Growth factors; Hepatocellular carcinoma; isocryptomerin; Kinases; Liver cancer; MAP kinase; Molecular modelling; Pharmacology; Reactive oxygen species; ROS; Signal transduction; Stat3 protein; Verification; isocryptomerin; cell cycle; ROS; cell apoptosis; cell migration; EGFR; hepatocellular carcinoma