Artemisinin alleviates obesity‐related glomerulopathy by downregulating CYP24A1 expression
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Published in | Diabetes, obesity & metabolism Vol. 26; no. 2; pp. 767 - 771 |
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Main Authors | , , , , , , , , , , , |
Format | Journal Article |
Language | English |
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Oxford, UK
Blackwell Publishing Ltd
01.02.2024
Wiley Subscription Services, Inc |
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Author | Cao, Tingbing Xiang, Jie Lang, Hongmei Jiang, Xiaoyan Gao, Peng Xiang, Li Chen, Xiaorong Mou, Aidi Zhu, Zhiming Lu, Zongshi Wang, Lijuan Zhang, Xingping |
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Author_xml | – sequence: 1 givenname: Xiaorong orcidid: 0000-0001-6769-8843 surname: Chen fullname: Chen, Xiaorong organization: Chengdu Second People's Hospital – sequence: 2 givenname: Jie orcidid: 0009-0005-8439-4928 surname: Xiang fullname: Xiang, Jie organization: Chengdu Second People's Hospital – sequence: 3 givenname: Peng surname: Gao fullname: Gao, Peng organization: Daping Hospital, Army Medical University, and Chongqing Institute of Hypertension – sequence: 4 givenname: Lijuan surname: Wang fullname: Wang, Lijuan organization: Daping Hospital, Army Medical University, and Chongqing Institute of Hypertension – sequence: 5 givenname: Li surname: Xiang fullname: Xiang, Li organization: Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences – sequence: 6 givenname: Zongshi surname: Lu fullname: Lu, Zongshi organization: Daping Hospital, Army Medical University, and Chongqing Institute of Hypertension – sequence: 7 givenname: Tingbing surname: Cao fullname: Cao, Tingbing organization: Daping Hospital, Army Medical University, and Chongqing Institute of Hypertension – sequence: 8 givenname: Aidi surname: Mou fullname: Mou, Aidi organization: Daping Hospital, Army Medical University, and Chongqing Institute of Hypertension – sequence: 9 givenname: Xingping surname: Zhang fullname: Zhang, Xingping organization: Chengdu Second People's Hospital – sequence: 10 givenname: Xiaoyan surname: Jiang fullname: Jiang, Xiaoyan organization: Chongqing University Central Hospital – sequence: 11 givenname: Zhiming orcidid: 0000-0001-6297-2962 surname: Zhu fullname: Zhu, Zhiming email: hbpcms@sina.com organization: Daping Hospital, Army Medical University, and Chongqing Institute of Hypertension – sequence: 12 givenname: Hongmei surname: Lang fullname: Lang, Hongmei email: junialang@sina.com organization: Chengdu Second People's Hospital |
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Cites_doi | 10.1038/cr.2016.108 10.1016/j.freeradbiomed.2018.12.017 10.1159/000530403 10.1046/j.1523-1755.2001.0590041498.x 10.1007/s11596-022-2564-x 10.7326/0003-4819-144-1-200601030-00006 10.1016/j.pharmthera.2020.107696 10.1155/2022/5401760 10.1038/sj.ki.5002796 10.1046/j.1523-1755.2000.00836.x 10.1038/ki.2008.453 10.1146/annurev-physiol-020911-153238 |
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Keywords | artemisinin CYP24A1 inflammation podocyte injury obesity-related glomerulopathy vitamin D |
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Notes | Hongmei Lang is the lead contact. Xiaorong Chen and Jie Xiang should be considered joint first authors. SourceType-Other Sources-1 content type line 63 ObjectType-Correspondence-1 |
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References_xml | – volume: 74 start-page: 299 year: 2012 end-page: 323 article-title: Cell biology and pathology of podocytes publication-title: Annu Rev Physiol – volume: 57 start-page: 167 year: 2000 end-page: 182 article-title: Early events leading to renal injury in obese Zucker (fatty) rats with type II diabetes publication-title: Kidney Int – volume: 74 start-page: 1343 year: 2008 end-page: 1353 article-title: Reduction of the vitamin D hormonal system in kidney disease is associated with increased renal inflammation publication-title: Kidney Int – volume: 73 start-page: 947 year: 2008 end-page: 955 article-title: Renal injury in the extremely obese patients with normal renal function publication-title: Kidney Int – volume: 42 start-page: 1022 year: 2022 end-page: 1032 article-title: CYP24A1 involvement in inflammatory factor regulation occurs via the Wnt signaling pathway publication-title: Curr Med Sci – volume: 144 start-page: 21 year: 2006 end-page: 28 article-title: Body mass index and risk for end‐stage renal disease publication-title: Ann Intern Med – volume: 216 year: 2020 article-title: The potential of artemisinins as anti‐obesity agents via modulating the immune system publication-title: Pharmacol Ther – volume: 131 start-page: 376 year: 2019 end-page: 381 article-title: Glutathione deficiency alters the vitamin D‐metabolizing enzymes CYP27B1 and CYP24A1 in human renal proximal tubule epithelial cells and kidney of HFD‐fed mice publication-title: Free Radic Biol Med – volume: 2022 year: 2022 article-title: Protective effect and possible mechanisms of Artemisinin and its derivatives for diabetic nephropathy: a systematic review and meta‐analysis in animal models publication-title: Oxid Med Cell Longev – volume: 26 start-page: 1169 year: 2016 end-page: 1172 article-title: Artemisinin derivatives prevent obesity by inducing browning of WAT and enhancing BAT function publication-title: Cell Res – volume: 59 start-page: 1498 year: 2001 end-page: 1509 article-title: Obesity‐related glomerulopathy: an emerging epidemic publication-title: Kidney Int – volume: 48 start-page: 314 year: 2023 end-page: 325 article-title: Vitamin D ameliorates podocyte injury by enhancing autophagy activity in diabetic kidney disease publication-title: Kidney Blood Press Res – ident: e_1_2_9_8_1 doi: 10.1038/cr.2016.108 – ident: e_1_2_9_7_1 doi: 10.1016/j.freeradbiomed.2018.12.017 – ident: e_1_2_9_11_1 doi: 10.1159/000530403 – ident: e_1_2_9_2_1 doi: 10.1046/j.1523-1755.2001.0590041498.x – ident: e_1_2_9_13_1 doi: 10.1007/s11596-022-2564-x – ident: e_1_2_9_3_1 doi: 10.7326/0003-4819-144-1-200601030-00006 – ident: e_1_2_9_5_1 doi: 10.1016/j.pharmthera.2020.107696 – ident: e_1_2_9_6_1 doi: 10.1155/2022/5401760 – ident: e_1_2_9_9_1 doi: 10.1038/sj.ki.5002796 – ident: e_1_2_9_10_1 doi: 10.1046/j.1523-1755.2000.00836.x – ident: e_1_2_9_12_1 doi: 10.1038/ki.2008.453 – ident: e_1_2_9_4_1 doi: 10.1146/annurev-physiol-020911-153238 |
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SubjectTerms | Antiparasitic agents Artemisinin Artemisinins - metabolism CYP24A1 Gene expression Humans inflammation Kidney diseases Obesity Obesity - complications Obesity - drug therapy Obesity - metabolism obesity‐related glomerulopathy podocyte injury Podocytes - metabolism vitamin D Vitamin D - metabolism Vitamin D3 24-Hydroxylase - metabolism |
Title | Artemisinin alleviates obesity‐related glomerulopathy by downregulating CYP24A1 expression |
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