AMPK activation modulates IL‐36‐induced inflammatory responses by regulating IκBζ expression in the skin - Huang, Yi‐Ting; Chiu, Ling‐Ya; Lu, Po‐Hsuan; Hsiao, Pa‐Fan; Wang, Jen‐Yu; Lu, Ping‐Hsun; Wu, Nan‐Lin (British journal of pharmacology, 2024)
Keywords: Adaptor Proteins, Signal Transducing; Aminoimidazole Carboxamide - analogs & derivatives; Aminoimidazole Carboxamide - pharmacology; AMP-activated protein kinase; AMP-Activated Protein Kinases - metabolism; AMPK; Animal models; Animals; Antimicrobial peptides; Cell activation; Cell culture; Cells, Cultured; Chemokine CCL20 - metabolism; Energy metabolism; Enzyme Activation - drug effects; Gene expression; Humans; Inflammation - drug therapy; Inflammation - metabolism; Inflammatory diseases; Interleukin-1 - metabolism; Interleukin-8 - metabolism; interleukin‐36; IκBζ; keratinocyte; Keratinocytes; Keratinocytes - drug effects; Keratinocytes - metabolism; Kinases; Leukocytes (neutrophilic); Mice; Mice, Inbred BALB C; Phosphorylation; Proteasomes; Protein expression; Protein turnover; Proteins; Psoriasis; pustular psoriasis; Ribonucleotides - pharmacology; skin; Skin - drug effects; Skin - metabolism; Skin - pathology; Skin diseases; Topical application; skin; AMPK; IκBζ; interleukin‐36; keratinocyte; pustular psoriasis