The roles of 5‐HT in orofacial pain

• Published in: Oral diseases Vol. 30; no. 6; pp. 3838 - 3849
• Main Authors: Zou, Zhishan, Fan, Wenguo, Liu, Haotian, Liu, Qing, He, Hongwen, Huang, Fang
• Format: Journal Article
• Language: English
• Published: Denmark Wiley Subscription Services, Inc 01.09.2024
• Subjects: 5‐HT; 5‐HT receptors; Animals; Chronic pain; Chronic Pain - drug therapy; Chronic Pain - metabolism; Chronic Pain - physiopathology; Facial Pain - drug therapy; Facial Pain - physiopathology; Humans; Monoamines; Neuromodulation; orofacial pain; Pain; pain modulation; Quality of life; Reviews; Serotonin - metabolism; Serotonin - physiology; orofacial pain; 5‐HT receptors; 5‐HT; pain modulation

Objectives Acute and chronic orofacial pain are very common and remain a vexing health problem that has a negative effect on the quality of life. Serotonin (5‐HydroxyTryptamine, 5‐HT) is a kind of monoamine neurotransmitter that is involved in many physiological and pathological processes. However,...