ALKBH5‐mediated m6A demethylation of pri‐miR‐199a‐5p exacerbates myocardial ischemia/reperfusion injury by regulating TRAF3‐mediated pyroptosis - Li, Jiarong; Wang, Zhirong; Tan, Huayi; Tang, Mi (Journal of biochemical and molecular toxicology, 2024)
Keywords: Adenine; AlkB Homolog 5, RNA Demethylase - genetics; AlkB Homolog 5, RNA Demethylase - metabolism; ALKBH5; Animals; Cell viability; Chromosome 5; Demethylation; Echocardiography; Flow cytometry; Heart function; Immunofluorescence; Immunohistochemistry; Immunoprecipitation; Injury prevention; Ischemia; Maturation; MI/RI; MicroRNAs - metabolism; Molecular modelling; Myocardial ischemia; Myocardial Reperfusion Injury - genetics; Myocardial Reperfusion Injury - metabolism; N6-methyladenosine; pri‐miR‐199a‐5p; Pyroptosis; Rats; Reperfusion; TNF Receptor-Associated Factor 3 - genetics; TNF Receptor-Associated Factor 3 - metabolism; TRAF3; Tumor necrosis factor receptors; Western blotting; pyroptosis; ALKBH5; MI/RI; TRAF3; pri‐miR‐199a‐5p