Clinical Pharmacokinetics of Oral ALZ-801/Valiltramiprosate in a 2-Year Phase 2 Trial of APOE4 Carriers with Early Alzheimer’s Disease - Hey, John A.; Yu, Jeremy Y.; Abushakra, Susan; Schaefer, Jean F.; Power, Aidan; Kesslak, Pat; Paul, Jijo; Tolar, Martin (Clinical pharmacokinetics, 2025)
Keywords: Administration, Oral; Aged; Alzheimer Disease - cerebrospinal fluid; Alzheimer Disease - drug therapy; Alzheimer Disease - genetics; Alzheimer's disease; Amyloid beta-Peptides; Apolipoprotein E4 - genetics; Apolipoproteins; Biomarkers; Biomarkers - cerebrospinal fluid; Body mass index; Clinical trials; Drug dosages; FDA approval; Female; Genotype & phenotype; Heterozygote; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Oral diseases; Original; Pharmacokinetics; Plasma; Prodrugs - administration & dosage; Prodrugs - pharmacokinetics; Taurine - analogs & derivatives