An updated review on diverse range of biological activities of 1,2,4-triazole derivatives: Insight into structure activity relationship

• Published in: Journal of molecular structure Vol. 1274; p. 134487
• Main Authors: Gupta, Ojasvi, Pradhan, Tathagata, Chawla, Gita
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 15.02.2023
• Subjects: 1,2,4-Triazole; Biological activity; Drug design; Heterocyclic chemistry; Structure-activity relationship; Synthesis; 1,2,4-Triazole; Heterocyclic chemistry; SAR; MIC; FST; EAC; PLK1; BRCA1/BRCA2; MPAK; FLT-3; MTT; PARP-1; TNF; Biological activity; MMP; Synthesis; Structure-activity relationship; VEGFR-2; HD50; LSD1; IC50; Drug design; PFU

•1,2,4-Triazole based aromatic and heterocyclic compounds holds tremendous potential in the medicinal chemistry.•Different biological targets for 1,2,4-triazole analogs have been discussed with their biological activity.•Synthetic strategy and SAR for the various biological activities of 1,2,4-triaz...