Intestinal absorption of bile acid glucuronides in rats

• Published in: Digestive diseases and sciences Vol. 33; no. 9; p. 1110
• Main Authors: Oelberg, D G, Little, J M, Adcock, E W, Lester, R
• Format: Journal Article
• Language: English
• Published: United States 01.09.1988
• Subjects: Animals; Bile Acids and Salts - metabolism; Cholic Acids - pharmacokinetics; Glucuronates - pharmacokinetics; Ileum - metabolism; Intestinal Absorption; Jejunum - metabolism; Lithocholic Acid - pharmacokinetics; Male; Rats; Rats, Inbred Strains; Taurocholic Acid - metabolism

While the intestinal absorption of taurine, glycine, and sulfate conjugates of bile acids has been studied extensively, nothing is known about the absorption of bile acid glucuronides. In the present study, the intestinal phase of the enterohepatic circulation of two bile acid glucuronides was exami...