Clinical outcomes for chest pain patients discharged home from emergency departments using high-sensitivity versus conventional cardiac troponin assays

• Published in: The American heart journal Vol. 221; pp. 84 - 94
• Main Authors: Lau, Geoffrey, Koh, Maria, Kavsak, Peter A., Schull, Michael J., Armstrong, David W.J., Udell, Jacob A., Austin, Peter C., Wang, Xuesong, Ko, Dennis T.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.03.2020; Elsevier Limited
• Subjects: Acute Coronary Syndrome - complications; Acute Coronary Syndrome - diagnosis; Acute Coronary Syndrome - metabolism; Adult; Aged; Aged, 80 and over; Ambulatory care; Angina; Angina pectoris; Angina, Unstable - epidemiology; Assaying; Calcium-binding protein; Cardiovascular diseases; Chest; Chest Pain - etiology; Clinical Laboratory Techniques - methods; Clinical outcomes; Comorbidity; Coronary artery disease; Diabetes; Diabetes mellitus; Emergency medical care; Emergency medical services; Emergency Service, Hospital; FDA approval; Female; Health hazards; Heart diseases; Heart failure; Hospitalization - statistics & numerical data; Humans; Hypertension; Information systems; Laboratories; Male; Middle Aged; Mortality; Myocardial infarction; Myocardial Infarction - epidemiology; Ontario - epidemiology; Pain; Patient Discharge; Patients; Personal health; Population; Prescription drugs; Proportional Hazards Models; Sensitivity; Troponin; Troponin I - analysis; Troponin I - metabolism; Troponin T - analysis; Troponin T - metabolism; Ontario; Canada; Ontario Canada; United States > US

High-sensitivity cardiac troponin (hs-cTn) assays enhance detection of lower circulating troponin concentrations, but the impact on outcomes in clinical practice is unclear. Our objective was to compare outcomes of chest pain patients discharged from emergency departments (EDs) using hs-cTn and conv...