Development of a nano-targeting chimera for the degradation of membrane and cytoplasmic proteins - Jin, Peipei; Chen, Zhaozheng; Zhang, Ju; Li, Haowen; Wei, Pengfei; Wang, Ziyu; Feng, Qiyu; Wang, Hongyang; Han, Da; Miao, Yanyan (Acta biomaterialia, 2025)
Keywords: Animals; Aptamer; Aptamers, Nucleotide - chemistry; Aptamers, Nucleotide - pharmacology; Autophagy; Autophagy-lysosome; Cancer therapy; Cell Line, Tumor; Cytoplasm - metabolism; Graphene oxide (GO); Graphite - chemistry; Graphite - pharmacology; Humans; Lysosomes - metabolism; Membrane Proteins - metabolism; Mice; Mice, Nude; Proteasome Endopeptidase Complex - metabolism; Proteolysis; Targeted protein degradation; Ubiquitin-proteasome; Aptamer; Graphene oxide (GO); Autophagy-lysosome; Targeted protein degradation; Cancer therapy; Ubiquitin-proteasome