Peptide PaDBS1R6 has potent antibacterial activity on clinical bacterial isolates and integrates an immunomodulatory peptide fragment within its sequence - Rezende, Samilla B.; Chan, Lai Yue; Oshiro, Karen G.N.; Buccini, Danieli F.; Leal, Ana Paula Ferreira; Ribeiro, Camila F.; Souza, Carolina M.; Brandão, Amanda L.O.; Gonçalves, Regina M.; Cândido, Elizabete S.; Macedo, Maria L.R.; Craik, David J.; et al. (Biochimica et biophysica acta. General subjects, 2024)
Keywords: Acinetobacter baumannii - drug effects; Anti-Bacterial Agents - chemistry; Anti-Bacterial Agents - pharmacology; Antibacterial peptides; Antimicrobial Peptides - chemistry; Antimicrobial Peptides - pharmacology; Biofilms - drug effects; Escherichia coli - drug effects; Humans; Immunomodulatory peptides; Microbial Sensitivity Tests; Molecular Dynamics Simulation; Peptide Fragments - chemistry; Peptide Fragments - pharmacology; Resistant bacteria; Wound healing; 10RMSD; 28MSD; 1AMP; 24PBS; 18MBC; 17MIC; Antibacterial peptides; 7MD; 14LACEN; 16MHB; 22FBS; 2APD; 9PME; 21DMEM; 30IM; 11RMSF; 3NCBI; Immunomodulatory peptides; 12Rg; Wound healing; 6NMR; 8DPC; 15MHA; 13CLSI; 19OD; 26SUV; 27SPR; 31OM; 29MBIC; 23MTT; 25DMSO; 5NO; Resistant bacteria; 4NR; 20CEUA