Rhinovirus Infection Induces Expression of Its Own Receptor Intercellular Adhesion Molecule 1 (ICAM-1) via Increased NF-κB-mediated Transcription

• Published in: The Journal of biological chemistry Vol. 274; no. 14; pp. 9707 - 9720
• Main Authors: Papi, Alberto, Johnston, Sebastian L.
• Format: Journal Article
• Language: English
• Published: 02.04.1999
• Subjects: Rhinovirus

Virus infections, the majority of which are rhinovirus infections, are the major cause of asthma exacerbations. Treatment is unsatisfactory, and the pathogenesis unclear. Lower airway lymphocyte and eosinophil recruitment and activation are strongly implicated, but the mechanisms regulating these pr...