Electroporation-derived melanoma extracellular particles activate fibroblasts

• Published in: Biochimica et biophysica acta. General subjects Vol. 1868; no. 12; p. 130723
• Main Authors: Choromańska, Anna, Szwedowicz, Urszula, Szewczyk, Anna, Daczewska, Małgorzata, Saczko, Jolanta, Kruszakin, Roksana, Pawlik, Krzysztof J., Baczyńska, Dagmara, Kulbacka, Julita
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.12.2024
• Subjects: Cell Line, Tumor; Cell Movement; Cell Survival; Electrochemotherapy - methods; Electroporation; Extracellular particles; Fibroblasts; Fibroblasts - metabolism; Histones - metabolism; Humans; Melanoma; Melanoma - metabolism; Melanoma - pathology; MMP-9; Vascular Cell Adhesion Molecule-1 - metabolism; VCAM-1; Fibroblasts; Electroporation; VCAM-1; MMP-9; Extracellular particles; Melanoma

Although the pulse electric field (PEF) has been used in electrochemotherapy (ECT) for many years, the kinetics and profile of extracellular particles (EPs) released as a result of reversible electroporation have yet to be studied. It also needs to be clarified whether and how the profile of release...