The effects of intravenous L-dopa on plasma renin activity, renal function, and blood pressure in man

• Published in: European journal of clinical pharmacology Vol. 35; no. 2; p. 137
• Main Authors: Worth, D, Harvey, J, Brown, J, Lee, M
• Format: Journal Article
• Language: English
• Published: Germany 01.01.1988
• Subjects: Adult; Blood Pressure - drug effects; Glomerular Filtration Rate - drug effects; Humans; Infusions, Intravenous; Kidney - drug effects; Kidney - physiology; Levodopa - administration & dosage; Levodopa - pharmacology; Male; Potassium - urine; Renal Circulation - drug effects; Renin - blood; Sodium - urine

L-dopa 7 micrograms.kg-1.min-1 was given intravenously over 2 h to six healthy subjects, controlled by an infusion of saline on a separate occasion, with measurement of plasma renin activity (PRA), urinary sodium and potassium excretion, effective renal plasma flow (ERPF), glomerular filtration rate...